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3-Epi-Ochratoxin C-d<sub>5</sub>

" in MedChemExpress (MCE) Product Catalog:

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5614

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

102

Peptides

MCE Kits

655

Inhibitory Antibodies

Natural
Products

2594

Recombinant Proteins

4252

Isotope-Labeled Compounds

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Antibodies

Click Chemistry

269

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W765059

3-Epi-Ochratoxin C-d5	Isotope-Labeled Compounds	Others
3-Epi-Ochratoxin C-d₅ is the deuterium labeled 3-Epi-Ochratoxin C.

HY-132380S

3-epi-Ochratoxin A-d5	Isotope-Labeled Compounds	Others
3-epi-Ochratoxin A-d₅ is the deuterium labeled 3-epi-Ochratoxin A .

HY-W754303

Dihydroartemisinin-13C,d5 Dihydroqinghaosu-¹³C,d<sub>5sub>; β-Dihydroartemisinin-¹³C,d<sub>5sub>; Artenimol-¹³C,d<sub>5sub>	Isotope-Labeled Compounds Apoptosis Autophagy Parasite NF-κB	Cancer
Dihydroartemisinin- ¹³C,d₅ (Dihydroqinghaosu- ¹³C,d₅) is the deuterium labeled and ¹³C-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.

HY-W018324S

5-Hydroxymethylcytosine-13C,d2 5hmC-¹³C,d<sub>2sub>	Isotope-Labeled Compounds	Others
5-Hydroxymethylcytosine- ¹³C,d₂ is the ¹³C and deuterium labeled 5-Hydroxymethylcytosine (HY-W018324) .

HY-W778290

5-Chloro-2-methoxy-benzoic Acid-13C,d3 5-Chloro-o-anisic acid (COOH=1)-¹³C,d<sub>3sub>; 5-Chloro-2-methoxybenzoic acid-¹³C,d<sub>3sub>	Isotope-Labeled Compounds	Others
5-Chloro-2-methoxy-benzoic Acid- ¹³C,d₃ (5-Chloro-o-anisic acid (COOH=1)- ¹³C,d₃) is the deuterium and ¹³C labeled 5-Chloro-2-methoxybenzoic acid (HY-W016163).

HY-165662S

Pranoprofen-13C-d3 Pyaopofe-¹³C-d<sub>3sub>; Y 8004-¹³C-d<sub>3sub>	Isotope-Labeled Compounds	Others
Pranoprofen- ¹³C-d₃ (Pyaopofe- ¹³C-d₃) is ¹³C and deuterium labeled Pranoprofen .

HY-B0202S4

Irbesartan-13C,d4 SR-47436-¹³C,d<sub>4sub>; BMS-186295-¹³C,d<sub>4sub>	Angiotensin Receptor Apoptosis Isotope-Labeled Compounds	Cardiovascular Disease
Irbesartan- ¹³C,d₄ (SR-47436- ¹³C,d₄; BMS-186295- ¹³C,d₄) is ¹³C-labeled Irbesartan (HY-B0202) .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-RS18793

Sub1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sub1 Mouse Pre-designed siRNA Set A Sub1 Mouse Pre-designed siRNA Set A

HY-RS25282

Sub1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sub1 Rat Pre-designed siRNA Set A Sub1 Rat Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-40354S2

Tofacitinib-13C,d3 Tasocitinib-¹³C,d<sub>3sub>; CP-690550-¹³C,d<sub>3sub>	Isotope-Labeled Compounds	Inflammation/Immunology Cancer
Tofacitinib- ¹³C,d₃ (Tasocitinib- ¹³C,d₃) is ¹³C labeled Tofacitinib. Tofacitinib is an orally available *JAK3/2/1* inhibitor with IC₅₀s of 1, 20, and 112 nM, respectively.

HY-15651S

Alvelestat-13C,d3 AZD9668-¹³C,d<sub>3sub>	Elastase Isotope-Labeled Compounds	Inflammation/Immunology
Alvelestat- ¹³C,d₃ (AZD9668- ¹³C,d₃) is ¹³C-labeled Alvelestat (HY-15651) .

HY-10219S1

Rapamycin-13C,d3 Sirolimus-¹³C,d<sub>3sub>; AY-22989-¹³C,d<sub>3sub>	Isotope-Labeled Compounds mTOR FKBP Autophagy	Cancer
Rapamycin- ¹³C,d₃ (Sirolimus- ¹³C,d₃; AY-22989- ¹³C,d₃) is the ¹³C and deuterium labeled Rapamycin (HY-10219) .Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .

HY-W011240S

Hydroflumethiazide-13C,d2 Methforylthiazidine-¹³C,d<sub>2sub>; Rontyl-¹³C,d<sub>2sub>	Isotope-Labeled Compounds	Others
Hydroflumethiazide- ¹³C,d₂ is the deuterium and ¹³C labeled Hydroflumethiazide .

HY-13318S1

Oseltamivir acid-13C,d3 GS 4071-¹³C,d<sub>3sub>; Ro 64-0802-¹³C,d<sub>3sub>; Oseltamivir carboxylate-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Drug Metabolite Influenza Virus	Infection
Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is a 13C- and deuterium-labeled Oseltamivir acid (HY-13318). Oseltamivir acid is the active metabolite of Oseltamivir phosphate and inhibits influenza virus neuraminidase (IC₅₀=2 nM). Oseltamivir acid is orally active and can be used to study influenza A/B infections ^[3] ^[5].

HY-W754842

Saxagliptin-13C,d2-1 hydrochloride BMS-477118-¹³C,d<sub>2sub> hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin- ¹³C,d₂-1 (BMS-477118- ¹³C,d₂) hydrochloride is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-W768856

Artemether-13C,d3 Dihydroqinghaosu methyl ether-¹³C,d<sub>3sub>; Dihydroartemisinin methyl ether-¹³C,d<sub>3sub>; SM224-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Parasite	Infection Inflammation/Immunology Cancer
Artemether- ¹³C,d₃ (Dihydroqinghaosu methyl ether- ¹³C,d₃) is the deuterium and ¹³C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-N0378S6

D-Mannitol-13C,d2 Mannitol-¹³C,d<sub>2sub>; Mannite-¹³C,d<sub>2sub>	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
D-Mannitol- ¹³C,d₂ is the deuterium and ¹³C labeled D-Mannitol.

HY-17016S3

Oseltamivir-13C,d3 phosphate GS 4104-¹³C,d<sub>3sub> phosphate	Isotope-Labeled Compounds Influenza Virus	Infection Cancer
Oseltamivir- ¹³C,d₃ (phosphate) (GS 4104- ¹³C,d₃ (phosphate)) is ¹³C labeled Oseltamivir (phosphate). Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

HY-W777599

(±)-Naproxen-13C,d3-1 (Rac)-Naproxen-¹³C,d<sub>3sub>-1	Isotope-Labeled Compounds	Others
(±)-Naproxen- ¹³C,d₃-1 ((Rac)-Naproxen- ¹³C,d₃-1) is ¹³C and deuterium labeled (±)-Naproxen .

HY-13693S2

Mometasone furoate-13C,d6 Sch32088-¹³C,d<sub>6sub>	Glucocorticoid Receptor Isotope-Labeled Compounds	Cancer
Mometasone furoate- ¹³C,d₆ (Sch32088- ¹³C,d₆) is ¹³C-labeled Mometasone furoate (HY-13693) .

HY-B0002BS2

Ondansetron-13C,d3 GR 38032-¹³C,d<sub>3sub>; SN 307-¹³C,d<sub>3sub>	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Ondansetron- ¹³C,d₃ is the ¹³C- and deuterium labeled Ondansetron .

HY-W777749

Methoxsalen-13C,d3 8-Methoxypsoralen-¹³C,d<sub>3sub>; Xanthotoxin-¹³C,d<sub>3sub>; 8-MOP-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Cytochrome P450	Cancer
Methoxsalen- ¹³C,d₃ (8-Methoxypsoralen- ¹³C,d₃) is the deuterium and ¹³C-labeled Methoxsalen (HY-30151). Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

HY-121309S1

Doxorubicinone-13C,d3 Adriamycin aglycone-¹³C,d<sub>3sub>; Adriamycinone-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Doxorubicinone- ¹³C,d₃ (Adriamycin aglycone- ¹³C,d₃) is ¹³C labeled Doxorubicinone. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin . Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively.

HY-B0330S2

Levofloxacin-13C,d3 (-)-Ofloxacin-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Levofloxacin- ¹³C,d₃ is the ¹³C- and deuterium labeled Levofloxacin.

HY-W768895

Sanguinarine chloride-13C,d3 Sanguinarin chloride-¹³C,d<sub>3sub>; Sanguinarium chloride-¹³C,d<sub>3sub>; Pseudochelerythrine chloride-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Apoptosis Bacterial Autophagy Parasite	Cancer
Sanguinarine chloride- ¹³C,d₃ (Sanguinarin chloride- ¹³C,d₃) is the deuterium labeled Sanguinarine chloride (HY-N0052A). Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d<sub>3sub>; AZT-¹³C,d<sub>3sub>; ZDV-¹³C,d<sub>3sub>	Isotope-Labeled Compounds HIV	Infection Cancer
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-B1455S1

Clindamycin-13C,d3	Isotope-Labeled Compounds Bacterial Antibiotic Parasite	Infection
Clindamycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria ^[3].

HY-B0740S1

Cyclobenzaprine-13C,d3 hydrochloride MK130-¹³C,d<sub>3sub> hydrochloride	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Cyclobenzaprine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Cyclobenzaprine (hydrochloride).

HY-B0192S1

Alfuzosin-13C,d3 SL 77499-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Adrenergic Receptor	Endocrinology
Alfuzosin- ¹³C,d₃ is the ¹³C- and deuterium labeled Alfuzosin.

HY-18252S

Avanafil-13C,d3 TA1790-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Phosphodiesterase (PDE)	Cardiovascular Disease
Avanafil- ¹³C,d₃ is the ¹³C- and deuterium labeled Avanafil.

HY-121259S

Doxorubicinol-13C,d3 TFA Adriamycinol-¹³C,d<sub>3sub> TFA; DXR-OL-¹³C,d<sub>3sub> TFA	Endogenous Metabolite	Others
Doxorubicinol- ¹³C,d₃ (TFA) is the deuterium and ¹³C labeled Doxorubicinol TFA .

HY-W777120

Cisapride-13C,d3 R 51619-13C,d3; (±)-Cisaprid-<sub>13<sub>C<sub>,d<sub>3<sub>	Isotope-Labeled Compounds 5-HT Receptor Potassium Channel	Neurological Disease
Cisapride- ¹³C,d₃ (R 51619- ¹³C,d₃) is the deuteriumand ¹³C-labeled Cisapride (HY-14149). Cisapride (R 51619) is an orally active 5-HT4 receptor agonist with an EC₅₀ value of 140 nM. Cisapride is a hERG blocker with an IC₅₀ value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity ^[3] .

HY-B0621S1

Triclabendazole-13C,d3 CGA89317-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Microtubule/Tubulin Parasite	Infection
Triclabendazole- ¹³C,d₃ is the ¹³C- and deuterium labeled Triclabendazole .

HY-17506S1

Azithromycin-13C,d3 CP 62993-¹³C,d<sub>3sub>	Bacterial Autophagy Antibiotic Isotope-Labeled Compounds	Others
Azithromycin- ¹³C,d₃ is the deuterium and ¹³C labeled Azithromycin .

HY-W011240S1

Hydroflumethiazide-15N2,13C,d2 Methforylthiazidine-¹⁵N<sub>2sub>,¹³C,d<sub>2sub>; Rontyl-¹⁵N<sub>2sub>,¹³C,d<sub>2sub>	Isotope-Labeled Compounds	Others
Hydroflumethiazide- ¹⁵N₂, ¹³C,d₂ is the ¹³C- and ¹⁵N-labeled Hydroflumethiazide .

HY-111772S

Elexacaftor-13C,d3 VX-445-¹³C,d<sub>3sub>	Isotope-Labeled Compounds	Inflammation/Immunology
Elexacaftor- ¹³C,d₃ is the deuterium labeled Elexacaftor (HY-111772) .

HY-10285S1

(rel)-Saxagliptin-13C,d2 TFA (rel)-BMS-477118-¹³C,d<sub>2sub> TFA	Dipeptidyl Peptidase Isotope-Labeled Compounds	Metabolic Disease
(rel)-Saxagliptin- ¹³C,d₂ ((rel)-BMS-477118- ¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285) .

HY-G0007S1

Omeprazole sulfone-13C,d3 Omeprazole sulfone-¹³C,d<sub>3sub>; Omeprazole sulphone-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Drug Metabolite	Others
Omeprazole metabolite Omeprazole sulfone- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole metabolite Omeprazole sulfone .

HY-10250S

Triciribine phosphate-13C,d3 TCN-P-¹³C,d<sub>3sub>	Isotope-Labeled Compounds	Others
Triciribine phosphate-- ¹³C,d₃ is the deuterium and ¹³C labeled Triciribine phosphate .

HY-10158S1

Bosutinib-13C,d3 SKI-606-¹³C<sub>,d<sub>3sub>	Isotope-Labeled Compounds Autophagy Bcr-Abl Src	Cancer
Bosutinib- ¹³C,d₃ (SKI-606- ¹³C,d₃) is ¹³C labeled Bosutinib. Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC₅₀ of 1.2 nM and 1 nM, respectively .

HY-13683S1

Mifepristone-13C,d3 RU486-¹³C,d<sub>3sub>; RU 38486-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Progesterone Receptor Glucocorticoid Receptor NO Synthase Autophagy	Endocrinology Cancer
Mifepristone- ¹³C,d₃ is the ¹³C- and deuterium labeled Mifepristone. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC₅₀s of 0.2 nM and 2.6 nM in in vitro assay . Mifepristone-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-19733S

Lumateperone-13C,d3 tosylate ITI-007-CH<sub>C,d<sub>3sub> tosylate	Isotope-Labeled Compounds Dopamine Receptor 5-HT Receptor	Neurological Disease Cancer
Lumateperone- ¹³C,d₃ (ITI-007- ¹³C,d₃) tosylate is ¹³C and deuterium labeled Lumateperone (tosylate). Lumateperone (ITI-007) tosylate is a *5-HT2A* receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia ^[3] .

HY-A0023AS

Alogliptin-13C,d3 SYR-322-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Dipeptidyl Peptidase	Metabolic Disease Cancer
Alogliptin- ¹³C,d₃ is the deuterium labeled Alogliptin. Alogliptin is a potent and selective inhibitor of DPP-4.

HY-10284S1

Linagliptin-13C,d3 BI 1356-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Dipeptidyl Peptidase Autophagy Ferroptosis	Metabolic Disease
Linagliptin- ¹³C,d₃ is the ¹³C- and deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Linagliptin-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0596S

Taltirelin-13C,d3 TA-0910-¹³C,d<sub>3sub>	Isotope-Labeled Compounds Thyroid Hormone Receptor Apoptosis	Neurological Disease Endocrinology
Taltirelin- ¹³C,d₃ (TA-0910- ¹³C,d₃) is ¹³C and deuterated labeled Taltirelin (HY-B0596). Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC₅₀ of 910 nM and EC₅₀ of 36 nM for stimulating an increase in cytosolic Ca ²⁺ concentration (Ca ²⁺ release).

HY-66011AS4

Moxifloxacin-13C,d3 hydrochloride BAY 12-8039-¹³C,d<sub>3sub>	Isotope-Labeled Compounds	Cancer
Moxifloxacin- ¹³C,d₃ hydrochloride (BAY 12-8039- ¹³C,d₃) is ¹³C and deuterated labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

HY-W765245

Rapamycin-13C,d3-1 Sirolimus-¹³C,d<sub>3sub>-1; AY-22989-¹³C,d<sub>3sub>-1	Isotope-Labeled Compounds Fungal mTOR Bacterial Autophagy Endogenous Metabolite FKBP Antibiotic	Cancer
Rapamycin- ¹³C,d₃-1 (Sirolimus- ¹³C,d₃-1) is the deuterium labeled and ¹³C-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 . Rapamycin is an autophagy activator, an immunosuppressant .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	Reference Standards NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-N13288

Cordysinin C/D	Structural Classification Alkaloids Animals Other Alkaloids Source classification	Parasite
Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain .

HY-125833R

Alpha-Naphthoflavone (Standard)	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone (Standard) is the analytical standard of Alpha-Naphthoflavone. This product is intended for research and analytical applications. Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N15356

9-Oxooctadecanedioic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Quercus suber L. Fagaceae	Bacterial
9-Oxooctadecanedioic acid is an α,ω-dicarboxylic fatty acid monomer found in the cork suberin of Quercus suber. It contributes to the formation of the hydrophobic barrier structure in plant cell walls and may play an important role in functions such as water resistance and protection against microbial penetration .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N15496

Fusaproliferin FUS	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Reactive Oxygen Species (ROS) NO Synthase Interleukin Related TNF Receptor p38 MAPK ERK IKK NF-κB
Fusaproliferin is a sesterterpene mycotoxin isolated from Fusarium solani. Fusaproliferin reverse Lipopolysaccharides (HY-D1056) stimulation and the NF-κB and MAPKs signaling pathways contribute to the anti-inflammatory process. Fusaproliferin exhibits affinity for the TLR4 protein with K_D values of 28.6 μM. Fusaproliferin shows cytotoxicity against pancreatic cancer cell with rapid and sub-micromolar IC₅₀ .

HY-W011370

Pelargonidin chloride	Structural Classification Anthocyans Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Plants Phaseolus vulgaris Linn. Disease Research Fields	Quinone Reductase Reactive Oxygen Species (ROS)
Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment ^[3].

HY-P2274R

Argifin (Standard)	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Parasite
Argifin (Standard) is the analytical standard of Argifin. This product is intended for research and analytical applications. Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].

HY-N0662R

Amentoflavone (Standard) Didemethyl-ginkgetin (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reference Standards Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-147089

PRRSV/CD163-IN-1	Infection Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Endogenous Metabolite
PRRSV/CD163-IN-1 is a *PRRSV/CD163* inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) .

HY-B0504S

Creatinine-d3 4 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Isotope-Labeled Compounds Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle .

HY-111054A

N-methyl-N-dithiocarboxyglucamine sodium MDCG sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound ¹⁰⁹Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity .

HY-B0579

Cyclosporin A Maximum Cited Publications 128 Publications Verification Cyclosporine A; Ciclosporin A; CsA	Structural Classification Natural Products Microorganisms Classification of Application Fields Anti-aging Source classification Inflammation/Immunology Disease Research Fields Cancer	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM ^[3]. Cyclosporin A also inhibits *CD11a/CD18* adhesion .

HY-N10445

Maydispenoid A	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	CD28 CD3
Maydispenoid A is a potent immunosuppressor. Maydispenoid A can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .

HY-111054

N-methyl-N-dithiocarboxyglucamine MDCG	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound ¹⁰⁹Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication .

HY-W020790

Sialyl-Lewis X sLeX	Structural Classification Polysaccharides Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .

HY-B0579R

Cyclosporin A (Standard) Cyclosporine A (Standard); Ciclosporin A (Standard); CsA (Standard)	Structural Classification Natural Products Microorganisms Source classification	Molecular Glues Reference Standards Complement System Antibiotic Cyclophilin
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM ^[3]. Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N10446

Maydispenoid B	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	CD28 CD3
Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .

HY-N3829

epi-Eudesmol	Structural Classification Terpenoids Sesquiterpenes Source classification Erythrina burttii Baker f. Plants Compositae	Others
epi-Eudesmol is a Sesquiterpenoids product that can be isolated from the leaves of Laggera alata var. montana C. D. Adams. .

HY-B0430B

(±)-Pantothenic acid (±)-Pantothenate; (±)-Vitamin B5	Other disease Disease markers Endogenous metabolite	Endogenous Metabolite
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice .

HY-N1115

Tubotaiwine (+)-Tubotaiwine; NSC 306222; Tubotaiwin	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Hunteria zeylanica Plants	Others
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling .

HY-106784

Ajoene	Infection Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Fungal Apoptosis
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .

HY-B0134B

Bestatin trifluoroacetate Ubenimex trifluoroacetate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin trifluoroacetate is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-B0134A

Bestatin hydrochloride 5+ Cited Publications Ubenimex hydrochloride	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-N5179

Chloropeptin II	Structural Classification Natural Products Microorganisms Source classification	HIV
Chloropeptin II inhibits the binding of gp120 to *CD4* with IC₅₀ of 3.3 μM, with the activity of selective anti-human immunodeficiency virus (HIV) .

HY-N5178

Chloropeptin I	Structural Classification Natural Products Microorganisms Source classification	HIV
Chloropeptin I inhibits the binding of gp120 to *CD4* with IC₅₀ of 2.0 μM, with the activity of selective anti-human immunodeficiency virus (HIV) .

HY-N15201

Betavulgarin	Structural Classification Natural Products Terpenoids Source classification Diterpenoids Beta vulgaris Linn. Plants Chenopodiaceae	STAT
Betavulgarin is an anticancer agent. Betavulgarin can be isolated from Sugar Beet (Beta vulgaris). Betavulgarin suppresses the proliferation, migration, colony formation, and mammosphere formation of breast cancer cells, and reduces the size of the CD44 ⁺/CD24 ⁻ subpopulation and the expression of the self-renewal- related genes C-Myc, Nanog and Oct4. Betavulgarin promotes BCSCs death through the regulation of Stat3/Sox2 signaling .

HY-B0134

Bestatin 5+ Cited Publications Ubenimex	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-N2362

DL-Alanine DL-2-Aminopropionic acid	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver ^[3] ^[5] .

HY-N10295

Flavipin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Aryl Hydrocarbon Receptor
Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4 ⁺ T cells and CD11b ⁺ macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA . Flavipin exhibits the DPPH free radical scavenging ability with IC₅₀ value of 7.2 μM, and has potent α-glucosidase inhibition with IC₅₀ value of 33.8 μM .

HY-B0134AR

Bestatin hydrochloride (Standard) Ubenimex hydrochloride (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Reference Standards Aminopeptidase Bacterial Antibiotic
Bestatin (hydrochloride) (Standard) is the analytical standard of Bestatin (hydrochloride). This product is intended for research and analytical applications. Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-N2940

Bisandrographolide A BAA	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	TRP Channel
Bisandrographolide A (BAA) activates TRPV4 channel with an EC₅₀ of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory, immunostimulant, and antihypertensive compound .

HY-N2109

Macranthoidin A	Triterpenes Structural Classification Caprifoliaceae Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Others
Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .

HY-N0640

Kuromanin chloride 5+ Cited Publications Chrysontemin; Cyanidin 3-O-glucoside chloride	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Moraceae Anthocyans Flavonoids Microorganisms Phenols Polyphenols Disease Research Fields Morus alba Linn.	CD38
Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities ^[3].

HY-B0134R

Bestatin (Standard) Ubenimex (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Reference Standards Aminopeptidase Bacterial Antibiotic
Bestatin (Standard) is the analytical standard of Bestatin. This product is intended for research and analytical applications. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-N12613

Sydowimide A	Structural Classification Natural Products Microorganisms Marine natural products Source classification Marine microorganism	SHP1 Phosphatase
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

HY-N2109R

Macranthoidin A (Standard)	Triterpenes Structural Classification Caprifoliaceae Terpenoids Source classification Plants	Reference Standards Others
Macranthoidin A (Standard) is the analytical standard of Macranthoidin A. This product is intended for research and analytical applications. Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .

HY-N0640R

Kuromanin chloride (Standard) Chrysontemin (Standard); Cyanidin 3-O-glucoside chloride (Standard)	Structural Classification Anthocyans Flavonoids Microorganisms Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	Reference Standards CD38
Kuromanin (chloride) (Standard) is the analytical standard of Kuromanin (chloride). This product is intended for research and analytical applications. Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities ^[3].

HY-15310

Ivermectin 25+ Cited Publications MK-933; CD-5024; K-237	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antiviral Anti-parasitic Disease Research Disease Research Fields Cancer	Flavivirus Dengue Virus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import ^[3] . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 ^[5].

HY-N15456

Cryptolepinone	Malvaceae Structural Classification Alkaloids Sida acuta Burm. F. Source classification Plants Indole Alkaloids	Quinone Reductase
Cryptolepinone is a quinone reductase activator with a CD (concentration required to double induction) value of 0.02 μg/mL and can be found in Sida acuta. In the mouse mammary organ culture assay, 10 μg/mL of Cryptolepinone inhibited 83.3% of the preneoplastic lesions induced by DMBA (HY-W011845). Cryptolepinone can be used in anti-cancer research .

HY-119347

Cirsilineol 3 Publications Verification	Laburnum anagyroides Medic. Structural Classification Monophenols Flavonoids Classification of Application Fields Flavones Source classification Phenols Plants Compositae Inflammation/Immunology Disease Research Fields	IFNAR STAT
Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4 ⁺ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-N9965

2'-Fucosyllactose 2'-FL	Infection Structural Classification Polysaccharides Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Saccharides	TNF Receptor Interleukin Related
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .

HY-116003

12,13-DiHOME	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
12,13-DiHOME is a stimulator of Brown adipose tissue (BAT), as well as a thermogenic lipokine that activates BAT in response to cold. (±)12,13-DiHOME activates BAT fuel uptake and enhances cold tolerance, via promoting the translocation of the FA transporters FATP1 and CD36 to the cell membrane. (±)12,13-DiHOME can be used for research of metabolic disorders .

HY-N0743

Senkyunolide A 2 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Umbelliferae Plants Disease Research Fields Cancer	α-synuclein
Senkyunolide A is a phthalide, anti-tumor cell proliferation agent with anticancer activity. Senkyunolide A protects neurons from corticosterone (HY-B1618)-induced apoptosis by decreasing protein phosphatase PP2A and α-synuclein phosphorylation and protein level. Senkyunolide A also inhibits osteoarthritis through the *NLRP3* signaling pathway and suppresses the expression of *CD137*, a diagnostic biomarker for atherosclerosis ^[3] ^[5].

HY-119347R

Cirsilineol (Standard)	Laburnum anagyroides Medic. Structural Classification Monophenols Flavonoids Flavones Source classification Phenols Plants Compositae	Reference Standards IFNAR STAT
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

Cat. No.	Product Name	Chemical Structure

HY-W765059

3-Epi-Ochratoxin C-d5
3-Epi-Ochratoxin C-d₅ is the deuterium labeled 3-Epi-Ochratoxin C.

HY-132380S

3-epi-Ochratoxin A-d5
3-epi-Ochratoxin A-d₅ is the deuterium labeled 3-epi-Ochratoxin A .

HY-W754303

Dihydroartemisinin-13C,d5
Dihydroartemisinin- ¹³C,d₅ (Dihydroqinghaosu- ¹³C,d₅) is the deuterium labeled and ¹³C-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.

HY-W018324S

5-Hydroxymethylcytosine-13C,d2
5-Hydroxymethylcytosine- ¹³C,d₂ is the ¹³C and deuterium labeled 5-Hydroxymethylcytosine (HY-W018324) .

HY-W778290

5-Chloro-2-methoxy-benzoic Acid-13C,d3
5-Chloro-2-methoxy-benzoic Acid- ¹³C,d₃ (5-Chloro-o-anisic acid (COOH=1)- ¹³C,d₃) is the deuterium and ¹³C labeled 5-Chloro-2-methoxybenzoic acid (HY-W016163).

HY-165662S

Pranoprofen-13C-d3
Pranoprofen- ¹³C-d₃ (Pyaopofe- ¹³C-d₃) is ¹³C and deuterium labeled Pranoprofen .

HY-B0202S4

Irbesartan-13C,d4
Irbesartan- ¹³C,d₄ (SR-47436- ¹³C,d₄; BMS-186295- ¹³C,d₄) is ¹³C-labeled Irbesartan (HY-B0202) .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-40354S2

Tofacitinib-13C,d3
Tofacitinib- ¹³C,d₃ (Tasocitinib- ¹³C,d₃) is ¹³C labeled Tofacitinib. Tofacitinib is an orally available *JAK3/2/1* inhibitor with IC₅₀s of 1, 20, and 112 nM, respectively.

HY-15651S

Alvelestat-13C,d3
Alvelestat- ¹³C,d₃ (AZD9668- ¹³C,d₃) is ¹³C-labeled Alvelestat (HY-15651) .

HY-10219S1

Rapamycin-13C,d3
Rapamycin- ¹³C,d₃ (Sirolimus- ¹³C,d₃; AY-22989- ¹³C,d₃) is the ¹³C and deuterium labeled Rapamycin (HY-10219) .Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .

HY-W011240S

Hydroflumethiazide-13C,d2
Hydroflumethiazide- ¹³C,d₂ is the deuterium and ¹³C labeled Hydroflumethiazide .

HY-13318S1

Oseltamivir acid-13C,d3
Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is a 13C- and deuterium-labeled Oseltamivir acid (HY-13318). Oseltamivir acid is the active metabolite of Oseltamivir phosphate and inhibits influenza virus neuraminidase (IC₅₀=2 nM). Oseltamivir acid is orally active and can be used to study influenza A/B infections ^[3] ^[5].

HY-W754842

Saxagliptin-13C,d2-1 hydrochloride
Saxagliptin- ¹³C,d₂-1 (BMS-477118- ¹³C,d₂) hydrochloride is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-W768856

Artemether-13C,d3
Artemether- ¹³C,d₃ (Dihydroqinghaosu methyl ether- ¹³C,d₃) is the deuterium and ¹³C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-N0378S6

D-Mannitol-13C,d2
D-Mannitol- ¹³C,d₂ is the deuterium and ¹³C labeled D-Mannitol.

HY-17016S3

Oseltamivir-13C,d3 phosphate
Oseltamivir- ¹³C,d₃ (phosphate) (GS 4104- ¹³C,d₃ (phosphate)) is ¹³C labeled Oseltamivir (phosphate). Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

HY-W777599

(±)-Naproxen-13C,d3-1
(±)-Naproxen- ¹³C,d₃-1 ((Rac)-Naproxen- ¹³C,d₃-1) is ¹³C and deuterium labeled (±)-Naproxen .

HY-13693S2

Mometasone furoate-13C,d6
Mometasone furoate- ¹³C,d₆ (Sch32088- ¹³C,d₆) is ¹³C-labeled Mometasone furoate (HY-13693) .

HY-B0002BS2

Ondansetron-13C,d3
Ondansetron- ¹³C,d₃ is the ¹³C- and deuterium labeled Ondansetron .

HY-W777749

Methoxsalen-13C,d3
Methoxsalen- ¹³C,d₃ (8-Methoxypsoralen- ¹³C,d₃) is the deuterium and ¹³C-labeled Methoxsalen (HY-30151). Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

HY-121309S1

Doxorubicinone-13C,d3
Doxorubicinone- ¹³C,d₃ (Adriamycin aglycone- ¹³C,d₃) is ¹³C labeled Doxorubicinone. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin . Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively.

HY-B0330S2

Levofloxacin-13C,d3
Levofloxacin- ¹³C,d₃ is the ¹³C- and deuterium labeled Levofloxacin.

HY-W768895

Sanguinarine chloride-13C,d3

Sanguinarine chloride- ¹³C,d₃ (Sanguinarin chloride- ¹³C,d₃) is the deuterium labeled Sanguinarine chloride (HY-N0052A). Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

HY-17413S1

Zidovudine-13C,d3
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-B1455S1

Clindamycin-13C,d3

Clindamycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria ^[3].

HY-B0740S1

Cyclobenzaprine-13C,d3 hydrochloride
Cyclobenzaprine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Cyclobenzaprine (hydrochloride).

HY-B0192S1

Alfuzosin-13C,d3
Alfuzosin- ¹³C,d₃ is the ¹³C- and deuterium labeled Alfuzosin.

HY-18252S

Avanafil-13C,d3
Avanafil- ¹³C,d₃ is the ¹³C- and deuterium labeled Avanafil.

HY-121259S

Doxorubicinol-13C,d3 TFA
Doxorubicinol- ¹³C,d₃ (TFA) is the deuterium and ¹³C labeled Doxorubicinol TFA .

HY-W777120

Cisapride-13C,d3
Cisapride- ¹³C,d₃ (R 51619- ¹³C,d₃) is the deuteriumand ¹³C-labeled Cisapride (HY-14149). Cisapride (R 51619) is an orally active 5-HT4 receptor agonist with an EC₅₀ value of 140 nM. Cisapride is a hERG blocker with an IC₅₀ value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity ^[3] .

HY-B0621S1

Triclabendazole-13C,d3
Triclabendazole- ¹³C,d₃ is the ¹³C- and deuterium labeled Triclabendazole .

HY-17506S1

Azithromycin-13C,d3
Azithromycin- ¹³C,d₃ is the deuterium and ¹³C labeled Azithromycin .

HY-W011240S1

Hydroflumethiazide-15N2,13C,d2
Hydroflumethiazide- ¹⁵N₂, ¹³C,d₂ is the ¹³C- and ¹⁵N-labeled Hydroflumethiazide .

HY-111772S

Elexacaftor-13C,d3
Elexacaftor- ¹³C,d₃ is the deuterium labeled Elexacaftor (HY-111772) .

HY-10285S1

(rel)-Saxagliptin-13C,d2 TFA
(rel)-Saxagliptin- ¹³C,d₂ ((rel)-BMS-477118- ¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285) .

HY-G0007S1

Omeprazole sulfone-13C,d3
Omeprazole metabolite Omeprazole sulfone- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole metabolite Omeprazole sulfone .

HY-10250S

Triciribine phosphate-13C,d3
Triciribine phosphate-- ¹³C,d₃ is the deuterium and ¹³C labeled Triciribine phosphate .

HY-10158S1

Bosutinib-13C,d3
Bosutinib- ¹³C,d₃ (SKI-606- ¹³C,d₃) is ¹³C labeled Bosutinib. Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC₅₀ of 1.2 nM and 1 nM, respectively .

HY-13683S1

Mifepristone-13C,d3

Mifepristone- ¹³C,d₃ is the ¹³C- and deuterium labeled Mifepristone. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC₅₀s of 0.2 nM and 2.6 nM in in vitro assay . Mifepristone-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-19733S

Lumateperone-13C,d3 tosylate

Lumateperone- ¹³C,d₃ (ITI-007- ¹³C,d₃) tosylate is ¹³C and deuterium labeled Lumateperone (tosylate). Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia ^[3] .

HY-A0023AS

Alogliptin-13C,d3
Alogliptin- ¹³C,d₃ is the deuterium labeled Alogliptin. Alogliptin is a potent and selective inhibitor of DPP-4.

HY-10284S1

Linagliptin-13C,d3
Linagliptin- ¹³C,d₃ is the ¹³C- and deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Linagliptin-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0596S

Taltirelin-13C,d3
Taltirelin- ¹³C,d₃ (TA-0910- ¹³C,d₃) is ¹³C and deuterated labeled Taltirelin (HY-B0596). Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC₅₀ of 910 nM and EC₅₀ of 36 nM for stimulating an increase in cytosolic Ca ²⁺ concentration (Ca ²⁺ release).

HY-66011AS4

Moxifloxacin-13C,d3 hydrochloride
Moxifloxacin- ¹³C,d₃ hydrochloride (BAY 12-8039- ¹³C,d₃) is ¹³C and deuterated labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

HY-W765245

Rapamycin-13C,d3-1
Rapamycin- ¹³C,d₃-1 (Sirolimus- ¹³C,d₃-1) is the deuterium labeled and ¹³C-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 . Rapamycin is an autophagy activator, an immunosuppressant .

HY-17410S2

Iloperidone-13C,d3
Iloperidone- ¹³C,d₃ (HP 873- ¹³C,d₃) is ¹³C labeled Iloperidone. Iloperidone (HP 873) is a *D₂/5-HT₂* receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms .

HY-B0251S1

Eplerenone-13C,d3

Eplerenone- ¹³C,d₃ (Epoxymexrenone- ¹³C,d₃) is ¹³C labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC₅₀ value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .

HY-14854S

Tecarfarin-13C,d3
Tecarfarin- ¹³C,d₃ (ATI-5923- ¹³C,d₃) is ¹³C labeled Tecarfarin. Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .

HY-B0389S25

D-Glucose-13C,d1
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig

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Species:	Human (1389) Rhesus Macaque (147) Rat (224) Bovine (1) Cynomolgus (268) E.coli (2) Rabbit (22) Canine (57) Pig (1) Rhesus Macaque/Cynomolgus (1) Marmoset (2) Mouse (498) Dog (2)
Tag:	SUMO (19) GST (20) Flag (57) GFP (2) His (1665) Tag Free (95) Strep (11) Avi (439) Myc (14) HSA (2) MBP (1) Trx (5) Fc (863) B2M (1)
Source:	HEK293 (2408) E. coli Cell-free (6) CHO (6) sf9 insect cells (1) CHO (13) Sf9 insect cells (3) P. pastoris (20) Sf9 insect cells (50) E. coli (86) sf9 insect cells (1)


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3-Epi-Ochratoxin C-d<sub>5</sub>

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