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  4. EMMPRIN/CD147 Protein, Canine (HEK293, His)

EMMPRIN/CD147 Protein, Canine (HEK293, His)

Cat. No.: HY-P703747
Handling Instructions Technical Support

EMMPRIN/CD147 Protein, Canine (HEK293, His) is the recombinant canine-derived EMMPRIN/CD147 protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

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Description

EMMPRIN/CD147 Protein, Canine (HEK293, His) is the recombinant canine-derived EMMPRIN/CD147 protein, expressed by HEK293, with C-His tag.
Background

EMMPRIN/CD147 is essential for normal retinal maturation and development (By similarity). It acts as a retinal cell surface receptor for NXNL1 and plays a critical role in NXNL1-mediated survival of retinal cone photoreceptors. In association with the glucose transporter SLC16A1/GLUT1 and NXNL1, it promotes retinal cone survival by enhancing aerobic glycolysis and accelerating glucose uptake into photoreceptors. Additionally, it may function as a potent stimulator of IL6 secretion in multiple cell lines, including monocytes.
Species

Canine
Source

HEK293
Tag

C-8*His
Accession

XP_533964 (A22-R205)
Protein Length

Partial
Predicted Molecular Mass
21.5 kDa
Molecular Weight

Approximately 30-45 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

EMMPRIN/CD147 Protein, Canine (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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