MedChemExpress (MCE) recombinant proteins encompass a comprehensive portfolio, including cytokines and growth factors, viral proteins, immune checkpoint proteins, CAR-T related proteins, CD antigens, receptor proteins, and enzymes. These proteins offer broad species coverage, spanning human, pig, dog, cattle, sheep, rabbit, cat, and model species like mouse, rat, Rhesus macaque, Cynomolgus macaque, Xenopus laevis. Engineered for multidisciplinary biological research, they feature diverse tag options such as His, GST, Fc, Sumo, and Flag.
Access 3,000 + Free Protein Samples
Up to 5 free samples per year — simple, fast, and always available.
•Website ordering: Find the product with the "Free Sample" option and click "Apply Now" !
•Email inquiring and Ordering:
Region Contact Email
Europe (including UK): eu.sales@medchemexpress.com
South Korea, Singapore, Malaysia, Indonesia, Australia, and New Zealand: sales@medchemexpress.cn
India: in.sales@medchemexpress.com
•Fill out the Application Form: Submit the quick form, and our sales team will contact you within 7 working days.
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Q&A
Q: How can I confirm if a product offers a free sample?
A: Products with a "Free Sample" option on the MCE website are eligible.
Categories Product Names / Cat. No.
Cytokines and Growth Factors IL-2
HY-P7037B		 TGFB1
HY-P7119		 IFN-gamma
HY-P7025		 EGF
HY-P7109
Immune Checkpoint Proteins PD-1
HY-P7395		 TIM-3
HY-P71995		 PD-L1
HY-P73361		 CD40
HY-P73499A
CAR-T Related Proteins MUC1
HY-P78774		 CA125
HY-P7696		 CD19
HY-P74328		 TROP-2
HY-P70457
CD Antigens CD3 epsilon
HY-P76788		 B7-1/CD80
HY-P7321		 CD155
HY-P76774		 CD4
HY-P72902
Fc Receptors FcRn
HY-P70601		 IgG1
HY-P73903		 IgE
HY-P77695		 Fc gamma RIIB
HY-P76235
Receptor Proteins GLP1R
HY-P70352		 Siglec-15
HY-P70742		 TrkB
HY-P70793		 Jagged-1/JAG1
HY-P71633
Enzymes & Regulators Cathepsin
HY-P7758A		 MMP-2
HY-P70268		 ACE2
HY-P73489		 ADAM10
HY-P702498
Complement System Complement C3/C3a
HY-P7863		 Complement Factor D
HY-P71726		 Complement C5/C5a
HY-P7695		 HABP1
HY-P76185
Ubiquitin Related Proteins UCHL1
HY-P73466		 RNF43
HY-P76008		 KEAP1
HY-P75897		 XIAP
HY-P73537
Biotinylated Proteins PCSK9 (Biotinylated)
HY-P78824		 SOST (Biotinylated)
HY-P78804		 DLL3 (Biotinylated)
HY-P78115		 CD47 (Biotinylated)
HY-P78561
Viral Proteins RSV Glycoprotein
HY-P75814		 Zika virus NS1
HY-P74455		 SARS-CoV-2 S RBD
HY-P74447		 Ebola virus VP40
HY-P76891
Animal-free
Recombinant Proteins 		Animal-Free GDF-2
HY-P700033AF		 Animal-Free GDNF
HY-P700084AF		 Animal-Free EGF
HY-P700051AF		 Animal-Free GM-CSF
HY-P700086AF
Product Bioactivity Data
The ED50 of human EGF (HY-P7109) was 53.08pg/mL, corresponding to a specific activity of 1.88 × 107units/mg, as determined by its effect on murine BALB/c 3T3 cells.
The ED50 of human Wnt Surrogate (HY-P70453C) from each lot of MCE is lower than that of Competitor P.
The ability of human Wnt Surrogate (HY-P70453C) to induce Topflash reporter activity in HEK293T human embryonic kidney cells was measured. The ED50 for this effect was found to be 5.2 ng/mL.
The ability of human noggin (HY-P7051A) to inhibit BMP-4-induced alkaline phosphatase production in ATDC5 cells was evaluated. An ED50 of 4 ng/mL was observed in the presence of 40 ng/mL Recombinant Human BMP-4.
Customer Validation in Psoriasis Research

Cited in: Liu W, et al. Theranostics. 2024 May 27;14(8):3339-3357.

Recombinant proteins IL-22 (HY-P77969), 1L-17 (HY-P700194AF), and TNF-α (HY-P70800) were used to construct an organoid model of inflammation to simulate the inflammatory environment of psoriasis. KEGG analysis revealed significant enrichment of glucose metabolism in psoriatic lesions and of OXPHOS pathway in IL17RA+ basal cells.
Customer Validation in Cancer Research
Under culture conditions supplemented with EGF (HY-P7109) and bFGF (HY-P7004), the human gastric adenocarcinoma cell line SGC7901 expressed hnRNPA2B1, a protein linked to cancer. In the lv-A2B1 group (overexpressing hnRNPA2B1 via lentivirus), tumor sphere formation was enhanced in both quantity and uniformity, indicating increased tumorigenic potential.

Cited in: Yang P, et al. Nat Commun. 2024 Sep 12;15(1):7996.

01
Codon
Optimization
02
Gene
Synthesis
03
Construction of
Expression Vector
04
Strain
Screening
05
Protein
Expression
06
Purification
& QC
07
Protein
Delivery
Please Note
This promotion, starts on July 1, 2025 , is exclusively available in Europe (including the UK), South Korea, Singapore, Malaysia, Indonesia, Australia, New Zealand, and India.
This offer can be combined with other promotions and is valid for end users only.
Each customer can request up to 5 free protein samples each year.
MedChemExpress reserves the right of final interpretation.