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Anti-infection
Antibiotic Arenavirus Bacterial
Beta-lactamase CHIKV CMV
Dengue Virus EBV Endoplasmic Reticulum Oxidoreductase 1 (ERO1)
Enterovirus Filovirus Flavivirus
Fungal HBV HCV
HCV Protease Hepatitis E Virus (HEV) HIV
HIV Protease HPV HSV
Influenza Virus Orthopoxvirus Parasite
Penicillin-binding protein (PBP) RABV Reverse Transcriptase
RSV SARS-CoV TMV
Tomato Spotted Wilt Virus (TSWV) Urease Virus Protease
VSV    
Antibody-drug Conjugate/ADC Related
ADC Antibody ADC Linker ADC Payload
Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) Drug-Linker Conjugates for ADC
Peptide-Drug Conjugates (PDCs) PROTAC-Linker Conjugates for PAC Radionuclide-Drug Conjugates (RDCs)
Apoptosis
Apoptosis ASK1 Bcl-2 Family
c-Myc Caspase Cuproptosis
DAPK Ferroptosis FKBP
Glutathione Peroxidase IAP MDM-2/p53
Necroptosis Paraptosis Photosensitizer
PKD Pyroptosis RIP kinase
Survivin Thymidylate Synthase TNF Receptor
Transferrin Receptor    
Autophagy
Atg4 Atg7 Atg8/LC3
ATTECs AUTACs Autophagy
Beclin1 ER-phagy FKBP
LRRK2 Mitophagy p62
PINK1/Parkin ULK  
Cell Cycle/DNA Damage
Antifolate APC ATF6
ATM/ATR Aurora Kinase Casein Kinase
CDK CDKL Checkpoint Kinase (Chk)
ClpP Cyclin G-associated Kinase (GAK) Deubiquitinase
DNA Alkylator/Crosslinker DNA Stain DNA-PK
DNA/RNA Synthesis Early 2 Factor (E2F) Endonuclease
Eukaryotic Initiation Factor (eIF) FKBP Folate Receptor (FR)
G-quadruplex Haspin Kinase HDAC
HMG Family HOXA HSP
IRE1 Kinesin LIM Kinase (LIMK)
MARK MASTL Microphthalmia Associated Transcription Factor (MITF)
Microtubule/Tubulin Microtubule‐associated serine/threonine kinase (MAST) Mps1
NEKs Nucleoside Antimetabolite/Analog p97
PAK PARP PDI
PERK Polo-like Kinase (PLK) Poly(ADP-ribose) Glycohydrolase (PARG)
PPAR RAD51 ROCK
Separase Sirtuin SRPK
STK33 SWI/SNF Complex Telomerase
TOPK Topoisomerase Wee1
YB-1 Zinc Finger Protein  
Cytoskeleton
Annexin A Arp2/3 Complex Cadherin
Cdc42-binding kinase Clathrin Claudin
Collagen Connexin Dynamin
Dystrophin Gap Junction Protein Integrin
Kinesin Lysyl Oxidase MARCKS
MASTL Microtubule/Tubulin Mps1
Myosin PAK ROCK
Tissue Factor Pathway Inhibitor (TFPI)    
Epigenetics
AMPK Aurora Kinase DNA Glycosylase
DNA Methyltransferase Epigenetic Reader Domain Glycosyltransferase
HDAC Histone Acetyltransferase Histone Demethylase
Histone Methyltransferase hnRNP HuR
JAK Methionine Adenosyltransferase (MAT) METTL3
MicroRNA PARP PKC
Protein Arginine Deiminase RNA MTase SF3B1
Sirtuin Small Interfering RNA (siRNA) TET Protein
WDR5 YTHDF  
GPCR/G Protein
5-HT Receptor Adenylate Cyclase Adhesion G Protein-coupled Receptors (AGPCRs)
Adrenergic Receptor Amylin Receptor Angiotensin Receptor
Apelin Receptor (APJ) Arf Family GTPase Arrestin
Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor
CaSR CCR CGRP Receptor
Chemerin Receptor Cholecystokinin Receptor CRFR
CXCR EBI2/GPR183 Endothelin Receptor
Formyl Peptide Receptor (FPR) Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor 1
G Protein-coupled Receptor Kinase (GRK) G2A (GPR132) GHSR
GLP Receptor GnRH Receptor GPR109A
GPR119 GPR139 GPR171
GPR35 GPR39 GPR4
GPR52 GPR55 GPR6
GPR65 GPR68 GPR84
GPR88 Guanylate Cyclase Histamine Receptor
Hydroxycarboxylic Acid Receptor (HCAR) ICMT Kisspeptin Receptor
Leukotriene Receptor LPL Receptor mAChR
Mas-related G-protein-coupled Receptor (MRGPR) MCHR1 (GPR24) Melanocortin Receptor
Melatonin Receptor mGluR Motilin Receptor
Natriuretic Peptide Receptor (NPR) Neurokinin Receptor Neuromedin U Receptor (NMUR)
Neuropeptide B/W Receptor Neuropeptide FF Receptor Neuropeptide S Receptor
Neuropeptide Y Receptor Neurotensin Receptor Olfactory Receptor
Opioid Receptor Orexin Receptor (OX Receptor) Orphan GPCR
Orphan Receptor Oxytocin Receptor P2Y Receptor
PACAP Receptor Platelet-activating Factor Receptor (PAFR) Prokineticin Receptor
Prostaglandin Receptor Protease Activated Receptor (PAR) PTHR
Ras RGS Protein RXFP Receptor
Secretin Receptor Somatostatin Receptor Succinate Receptor 1
Taste Receptor Trace Amine-associated Receptor (TAAR) TSH Receptor
Urotensin Receptor Vasopressin Receptor  
Immunology/Inflammation
AIM2 ALCAM/CD166 AP-1
Arginase Aryl Hydrocarbon Receptor Asialoglycoprotein Receptor (ASGPR)
BCL6 C-type Lectin-like Receptors (CTLRs) CCR
CD1 CD19 CD2
CD20 CD22 CD276/B7-H3
CD28 CD3 CD38
CD44 CD47 CD6
CD73 CD74 Complement System
COX CTLA-4 CX3CR1
CXCR Cyclic GMP-AMP Synthase Cyclophilin
DOCK E-Selectin FAP
Fc Receptor (FcR) FKBP FLAP
Galectin Glucocorticoid Receptor Glycoprotein VI
Histamine Receptor Human leukocyte immunoglobulin (Ig)-like receptors (LILR) IFNAR
IKZF Family Interleukin Related IRAK
Kallikrein L-Selectin LAG-3
Macrophage migration inhibitory factor (MIF) Mesothelin MHC
Mucin MyD88 Nectin-4
NO Synthase NOD-like Receptor (NLR) NTPDase
Nuclear Factor of activated T Cells (NFAT) Osteopontin P-selectin
PD-1/PD-L1 PGE synthase Programmed Cell Death 4 (PDCD4)
PSMA Pyroptosis Reactive Oxygen Species (ROS)
RIG-I-like receptor (RLR) S100 Protein Salt-inducible Kinase (SIK)
Scavenger Receptor Class B type I (SR-BI) SOD SphK
STING Thrombopoietin Receptor Tim3
Toll-like Receptor (TLR) Transmembrane Glycoprotein TREM receptor
TROP2 VAP-1  
JAK/STAT Signaling
EGFR JAK Pim
STAT    
MAPK/ERK Pathway
ABA Receptor ERK JNK
KLF MAP3K MAP4K
MAPKAPK2 (MK2) MEK Microtubule‐associated serine/threonine kinase (MAST)
Mixed Lineage Kinase MNK p38 MAPK
Raf Ras Ribosomal S6 Kinase (RSK)
SOS1    
Membrane Transporter/Ion Channel
Amino acid Transporter Anion Exchangers Apical Sodium-Dependent Bile Acid Transporter
Aquaporin ASCT ATP Synthase
ATP-binding cassette (ABC) transporters BCRP Calcium Channel
Calmodulin CFTR Chloride Channel
CRAC Channel CRM1 EAAT
EHD Protein FATP Ferlin Family
Ferroportin GABA Receptor GLUT
Glycine Receptor (GlyR) GlyT HCN Channel
iGluR Monoamine Transporter Monocarboxylate Transporter
Na+/Ca2+ Exchanger Na+/H+ Exchanger (NHE) Na+/HCO3- Cotransporter
Na+/K+ ATPase nAChR NKCC
Nucleoside Transporters OAT Oligopeptide Cotransporter
P-glycoprotein P2X Receptor Piezo Channel
Potassium Channel Proton Pump Sec61
SGLT SLC39 (Zinc Transporter) Sodium Channel
Sodium Phosphate Cotransporter Synaptic Vesicle Proteins TRP Channel
URAT1 Urea Transporter VDAC
WNK Kinase    
Metabolic Enzyme/Protease
11β-HSD 15-PGDH 17β-HSD
3β-HSD 5 alpha Reductase Acetolactate Synthase (ALS)
Acetyl-CoA Carboxylase Acetyl-CoA synthetase Acyltransferase
ADAMTS Adiponectin Receptor Aldehyde Dehydrogenase (ALDH)
Aldehyde Oxidase (AO) Aldose Reductase Amine N-methyltransferase
Amino Acid Oxidase Aminoacyl-tRNA Synthetase Aminopeptidase
Aminotransferases (Transaminases) Amylases Angiotensin-converting Enzyme (ACE)
ANGPTL Apolipoprotein Arginase
ATGL ATP Citrate Lyase BTB/POZ Family
Carbamoyl Phosphate Synthetase (CPS) Carbonic Anhydrase Carbonyl Reductase
Carboxylesterase (CES) Carboxypeptidase Carnosine-cleaving Enzyme
Cathepsin Ceramidase CETP
COMT Creatine Kinase Cryptochrome
Cytochrome P450 DAGL DGK
Dihydroceramide Desaturase 1 (DES1) Dihydrofolate reductase (DHFR) Dihydroorotate Dehydrogenase
Dihydropyrimidine Dehydrogenase (DPD) Dipeptidyl Peptidase Drug Metabolite
E1/E2/E3 Enzyme Elastase ELOVL
Emopamil Binding Protein Endogenous Metabolite Endothelin-Converting Enzyme (ECE)
Enolase Enteropeptidase Epoxide Hydrolase
FAAH FABP Factor VIIa
Factor VIII Factor Xa Factor XI
Farnesyl Transferase Fat Mass and Obesity-associated Protein (FTO) Fatty Acid Synthase (FASN)
FBPase Ferrochelatase FOXO
Furin FXR Galactokinase
GGTase GHR Glucokinase
Glucose-6-Phosphate Isomerase (GPI) Glutamate Dehydrogenase (GLDH) Glutaminase
Glutathione Peroxidase Glutathione Reductase (GR) Glutathione S-transferase
Glycolate Oxidase Glycosidase Glyoxalase (GLO)
GSNOR HCV Protease Heme Oxygenase (HO)
Hemoglobin Hepcidin Herbicide
Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase
HIV Protease HMG-CoA Reductase (HMGCR) HPPD
HRASLS HSP IDE
IMPDH Indoleamine 2,3-Dioxygenase (IDO) IPK Superfamily
Isocitrate Dehydrogenase (IDH) Ketohexokinase KMO
Lactate Dehydrogenase LDLR Lipase
Lipocalin Family Liposome Lipoxygenase
LOX-1 LXR MAGL
Malate Dehydrogenase (MDH) Malonyl-CoA Decarboxylase MALT1
MetAP Methionine Adenosyltransferase (MAT) Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Microsomal Triglyceride Transfer Protein (MTP) Mineralocorticoid Receptor Mitochondrial Metabolism
MMP N-myristoyltransferase NADH Dehydrogenase
NADPH Oxidase NAMPT NEDD8-activating Enzyme
Neprilysin Ornithine decarboxylase (ODC) Oxidative Phosphorylation
Oxysterol-binding Protein-related Protein (ORP) PAI-1 Palmitoyl Protein Thioesterase (PPT)
PANK Pantetheinase PCSK9
PDHK PDI PEPCK
PGC-1α Phosphatase Phosphodiesterase (PDE)
Phosphoglycerate Dehydrogenase (PHGDH) Phosphoglycerate Kinase (PGK) Phospholipase
Phosphomannose Isomerase (PMI) Phosphorylase Photosystem II
PI4P5K PI5P4K PNPLA3
PPAR Procollagen C Proteinase Prolyl Endopeptidase (PREP)
Proteasome Protein Prenyltransferase Proteolytic Enzyme
Protoporphyrinogen IX oxidase Pyruvate Carboxylase (PC) Pyruvate Kinase
Pyruvate Oxidase Quinone Reductase RAR/RXR
Reactive Oxygen Species (ROS) Renin REV-ERB
ROR RPE65 Ser/Thr Kinase
Ser/Thr Protease Serine Racemase (SR) Serpin
Sex Pheromone SGK SHMT
Sialyltransferase SPFH Protein Superfamily Stearoyl-CoA Desaturase (SCD)
Steroid Sulfatase Succinate Dehydrogenase SULT
Thrombin TMPRSS6 Transglutaminase
Transketolase TrxR Tryptophan Hydroxylase
Tyrosinase Tyrosine Hydroxylase UGT
Xanthine Oxidase β-glucuronidase γ-Glutamyl Transferase (GGT)
Neuronal Signaling
5-HT Receptor AAK1 Adrenergic Receptor
Amino Acid Decarboxylase Amyloid-β Beta-secretase
Calcineurin Calcium Channel CaMK
Cannabinoid Receptor CGRP Receptor Cholecystokinin Receptor
Choline Kinase Cholinesterase (ChE) COMT
Dihydroceramide Desaturase 1 (DES1) Dimethylargininase (DDAH) FAAH
GABA Receptor Glucosylceramide Synthase (GCS) GlyT
GPR119 GPR139 GPR55
Histamine Receptor Huntingtin iGluR
Imidazoline Receptor Legumain mAChR
MCHR1 (GPR24) Melanocortin Receptor Melatonin Receptor
mGluR Monoamine Oxidase nAChR
Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor
Notch OGA OGT
Olfactory Receptor OLIG2 Opioid Receptor
Orexin Receptor (OX Receptor) PINK1/Parkin Prion Protein
Serotonin Transporter Sigma Receptor Slit Proteins
Somatostatin Receptor Tau Protein Transthyretin (TTR)
Trk Receptor TRP Channel TSPO
α-synuclein γ-secretase  
NF-κB
IKK Keap1-Nrf2 MALT1
Microtubule‐associated serine/threonine kinase (MAST) NF-κB RANKL/RANK
Reactive Oxygen Species (ROS)    
PI3K/Akt/mTOR
Akt AMPK ATM/ATR
DNA-PK GSK-3 IPK Superfamily
MELK Microtubule‐associated serine/threonine kinase (MAST) mTOR
PDK-1 PI3K PI4K
PIKfyve PIN1 PTEN
PROTAC
ATTECs AUTACs AUTOTACs
ByeTAC E3 Ligase Ligand-Linker Conjugates Ligands for E3 Ligase
Ligands for Target Protein for PROTAC LYTACs Molecular Glues
PROTAC Linkers PROTAC-Linker Conjugates for PAC PROTACs
SNIPERs Target Protein Ligand-Linker Conjugates  
Protein Tyrosine Kinase/RTK
Ack1 Anaplastic lymphoma kinase (ALK) Bcr-Abl
BMX Kinase BRK Btk
c-Fms c-Kit c-Met/HGFR
Discoidin Domain Receptor DYRK EGFR
Ephrin Receptor FAK FGFR
FLT3 GDNF Receptor IGF-1R
Itk JAK PDGFR
Pyk2 RET ROS Kinase
SHP1 SHP2 Src
Syk TAM Receptor Tie
TNK1 Trk Receptor VEGFR
Stem Cell/Wnt
BMI1 Casein Kinase Connective Peptide
ERK Gli GSK-3
Hedgehog Hippo (MST) JAK
Notch Oct3/4 Organoid
PKA PKG Porcupine
ROCK RUNX SDCBP
sFRP-1 Smo STAT
TGF-beta/Smad Wnt YAP
β-catenin γ-secretase  
TGF-beta/Smad
Dan family PKA PKC
ROCK RUNX TGF-beta/Smad
TGF-β Receptor    
Vitamin D Related/Nuclear Receptor
Androgen Receptor Constitutive Androstane Receptor Estrogen Receptor/ERR
Glucocorticoid Receptor LXR Mineralocorticoid Receptor
Nuclear Hormone Receptor 4A/NR4A Orphan Nuclear Receptor PPAR
Pregnane X Receptor (PXR) Progesterone Receptor RAR/RXR
REV-ERB ROR Thyroid Hormone Receptor
VD/VDR VKOR  
Others
Amino Acid Derivatives Biochemical Assay Reagents Drug Derivative
Drug Intermediate Drug Isomer Fluorescent Dye
Insecticide Isotope-Labeled Compounds mRNA
Phytohormone Reference Standards Others