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Multi-Target Compound Library

Cat. No.: HY-L176

The occurrence of diseases is often associated with multiple targets and pathways, and the factors of disease formation are complex and diverse, so the development of more powerful drugs is needed. According to statistics, 21% of the FDA-approved drugs in 2015-2017 were multi-target compounds. Multi-target compounds refer to a drug targeting multiple disease-related targets or multiple subtypes of a target. Multi-target compounds can be applied to drug screening or targeted ligand design. Because the targets of such compounds are diverse and clear, they have the characteristics of saving time and drug cost during the mechanism research of new drug research and development. In addition, due to the diversity of drug targets, multiple strategies can be applied to pharmacological studies.

MCE supplies a unique collection of 4,561 multi-target compounds that targets two or more different targets or different subtypes of the same target. MCE Multi-Target Compound Library can be used for target protein ligand screening or drug development.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Widely used in the research focus areas such as Cancer, Stem Cell, Neuronal Signaling, Immunity, and more.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 4,561 multi-target compounds supplied as pre-dissolved Solutions or Solid.
Solution: 4,467 compounds supplied in 10 mM solution, 84 compounds supplied in 2 mM solution, 10 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

NF-κB (217)

CDK (181)

HIV (174)

PI3K (165)

COX (147)

EGFR (132)

Akt (129)

VEGFR (129)

Fungal (111)

ERK (99)

mTOR (98)

JAK (94)

HDAC (92)

PDGFR (81)

PPAR (75)

FGFR (74)

PARP (74)

MMP (72)

STAT (72)

FLT3 (64)

PKC (60)

mAChR (59)

Wnt (58)

HSV (57)

c-Kit (54)

GSK-3 (52)

HCV (52)

Src (51)

ROCK (47)

JNK (45)

AMPK (44)

mGluR (43)

iGluR (42)

Raf (39)

HBV (38)

HSP (36)

MEK (36)

IKK (31)

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  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Multi-Target Compound Library
    Cat. No.:
    HY-L176
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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