1. Customized Service
  2. Gene Regulation Tool

Gene Regulation Tool

Viral vectors are essential tools in molecular biology, enabling efficient delivery of target genes into both cultured cells and entire living organisms. Their infection efficiency of these viral vectors typically surpasses that of plasmid transfection, especially for hard-to-transfect cell types such as primary cells and stem cells. This makes viral vectors crucial for overexpressing exogenous genes and conducting gene knockdown. Commonly used viral vectors include lentiviral vectors (LV), adenoviral vectors (AdV), and adeno-associated virus vectors (AAV).

MedChemExpress leverages established viral vector manufacturing techniques to offer a comprehensive range of lentiviral and adenoviral packaging services, suitable for manipulating both coding and non-coding genes. Our virus production process follow internationally recognized standards, ensuring delivered viral products meet titer specifications and are free from contamination, which guarantees suitability for a diverse range of experimental requirements.

Key Features of Different Viral Vectors
Lentivirus Adenovirus Adeno-Associated Virus
Genome dsRNA dsDNA ssDNA
Is DNA integrated
into host genome?
Yes No No
Transgene size < 4 kb < 7 kb < 4 kb
Titer 108-109 TU/mL 1010-1011 PFU/mL 1012-1013 VG/mL
Transgene expression Stable Transient Stable/Transient
Immune response High High Low
Advantages The gene transfer is long-lasting in most
cell types. Suitable for the construction of
stable cell lines.
Efficient transduction for most cell types.
Large packaging capacity
Non-inflammatory and
non-pathogenic, suitable for
animal experiments
Advantages
Service Consultation
Virus packaging custom services require evaluation to determine the appropriate scheme and pricing. For additional information about service price and technical specifics, please send an email to sales@MedChemExpress.com or contact the sales staff of MedChemExpress directly.