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Antioxidant Compound Library

Cat. No.: HY-L037

Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue damage. Oxidative stress can be responsible for the induction of several diseases, both chronic and degenerative, as well as speeding up body aging process and cause acute pathologies. Antioxidants are a class of compounds able to counteract oxidative stress and mitigate its effects on individuals’ health, gained enormous attention from the biomedical research community. Antioxidants have long been substantial and amenable therapeutic arsenals for multifarious diseases such as AD and cancer.

MCE Antioxidant Compound Library contains 1,609 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS). This library is a useful tool for discovery new antioxidants and oxidative stress research.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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Description & Advantages

•   A unique collection of 1,609 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as NF-κB, mTOR, Keap1-Nrf2, AMPK, Sirtuin, etc.

•   Bioactivity and safety confirmed by preclinical research and clinical trials, some compounds have been approved by FDA.

•   A useful tool to study oxidative stress.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 1,609 antioxidants supplied as pre-dissolved Solutions or Solid
Solution: 1,571 compounds supplied in 10 mM solution, 27 compounds supplied in 2 mM solution, 11 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

NF-κB (303)

mTOR (105)

AMPK (81)

PI3K (51)

COX (46)

Akt (45)

ERK (28)

HIV (24)

PPAR (20)

MMP (17)

STAT (15)

JNK (14)

HBV (10)

HSV (10)

JAK (10)

IKK (8)

PARP (8)

SOD (8)

Wnt (8)

AP-1 (7)

HCV (7)

HSP (7)

HDAC (6)

CDK (5)

FAK (5)

AIM2 (4)

EGFR (4)

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  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Antioxidant Compound Library
    Cat. No.:
    HY-L037
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack