2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. TNK1

TNK1

Tyrosine kinase non receptor 1; KOS1

 

TNK1 Related Products (9):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-14443
    XMD8-92
    		Inhibitor 99.48%
    XMD8-92 is a potent ERK5 (BMK1)/BRD4 inhibitor with Kds of 80 and 190 nM, respectively. XMD8-92 inhibits DCAMKL2, PLK4 and TNK1 with Kds of 190, 600 and 890 nM, respectively. Anti-cancer activity.
    XMD8-92
  • HY-147316
    TP-5801
    		Inhibitor 99.69%
    TP-5801 is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity.
    TP-5801
  • HY-15800A
    CZC-25146
    		Inhibitor 99.10%
    CZC-25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 can increase normal α-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 can be used to research Parkinson's disease and liver diseases.
    CZC-25146
  • HY-147316A
    TP-5801 TFA
    		Inhibitor 99.34%
    TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity.
    TP-5801 TFA
  • HY-153259
    TNKS1/2-IN-2
    		Inhibitor
    TNKS1/2-IN-2 (Compound 21) is a potent and selective tankyrases inhibitor. TNKS1/2-IN-2 exhibits IC50 values of 4 nM and 63 nM against TNK1 and TNK2 in the enzymatic assay, respectively. TNKS1/2-IN-2 inhibits proliferation of A549 and H292 cell lines with IC50 values of 39.5 nM and 12.8 nM, respectively. TNKS1/2-IN-2 can be used for the research of cancer.
    TNKS1/2-IN-2
  • HY-RS14837
    TNK1 Human Pre-designed siRNA Set A
    		Inhibitor

    TNK1 Human Pre-designed siRNA Set A contains three designed siRNAs for TNK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TNK1 Human Pre-designed siRNA Set A
    TNK1 Human Pre-designed siRNA Set A
  • HY-15800
    CZC-25146 hydrochloride
    		Inhibitor
    CZC-25146 hydrochloride is a potent LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 hydrochloride inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 hydrochloride prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 hydrochloride exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 hydrochloride can increase normal α-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 hydrochloride can be used to research Parkinson's disease and liver diseases.
    CZC-25146 hydrochloride
  • HY-RS18502
    Tnk1 Mouse Pre-designed siRNA Set A
    		Inhibitor

    Tnk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Tnk1 Mouse Pre-designed siRNA Set A
    Tnk1 Mouse Pre-designed siRNA Set A
  • HY-RS24984
    Tnk1 Rat Pre-designed siRNA Set A
    		Inhibitor

    Tnk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tnk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Tnk1 Rat Pre-designed siRNA Set A
    Tnk1 Rat Pre-designed siRNA Set A