2. Cytoskeleton Immunology/Inflammation
  3. Integrin CD22
  4. Pinatuzumab

Pinatuzumab is a humanized monoclonal antibody targeting cell-surface antigen CD22. Pinatuzumab can be used to synthesize antibody-drug conjugate (ADC) such as Pinatuzumab vedotin (HY-141602). Pinatuzumab can be studied in research on cancer such as non-Hodgkin lymphoma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

CAS No. : 1639820-81-7

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Based on 1 publication(s) in Google Scholar

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

Pinatuzumab is a humanized monoclonal antibody targeting cell-surface antigen CD22. Pinatuzumab can be used to synthesize antibody-drug conjugate (ADC) such as Pinatuzumab vedotin (HY-141602). Pinatuzumab can be studied in research on cancer such as non-Hodgkin lymphoma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001)[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Humanized

In Vivo

Pinatuzumab is the monoclonal antibody part of the antibody-drug conjugate Pinatuzumab vedotin, which can be used in B-cell non-Hodgkin’s lymphoma research[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

146.69 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Pinatuzumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized Siglec-2/CD22 Protein, Human can bind Pinatuzumab. The EC50 for this effect is 4.017 ng/mL.
Purity & Documentation
References
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Pinatuzumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pinatuzumab1639820-81-7IntegrinCD22Siglec 2monoclonal antibodyantibody drug conjugates (ADCs)non-Hodgkin lymphoma (NHL)tumorInhibitorinhibitorinhibit

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