2. Recombinant Proteins
  3. Cytokines and Growth Factors CD Antigens
  4. Interleukin & Receptors T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins
  5. IL-2 Receptor IL-2R alpha/CD25 IL-2R alpha/CD25
  6. IL-2R alpha/CD25
  7. IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His)

IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His)

Cat. No.: HY-P704702
Handling Instructions Technical Support

IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His) is the recombinant cynomolgus-derived IL-2R alpha/CD25 protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

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Description

IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His) is the recombinant cynomolgus-derived IL-2R alpha/CD25 protein, expressed by HEK293, with C-His tag.
Background

IL-2R alpha/CD25 is a receptor for interleukin-2, involved in regulating immune tolerance by controlling the activity of regulatory T cells (TREGs). TREGs suppress the activation and expansion of autoreactive T-cells.
Species

Cynomolgus
Source

HEK293
Tag

C-His
Accession

H6WS54 (E22-E238)
Gene ID

102123605
Molecular Construction
N-term
IL-2Rα (E22-E238)
Accession # H6WS54
His
C-term
Synonyms
CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR
Predicted Molecular Mass
26.3 kDa.
Molecular Weight

Approximately 43-55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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