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  3. Adenosine monophosphate-13C10,15N5 disodium

Adenosine monophosphate-13C10,15N5 disodium  (Synonyms: AMP-13C10,15N5 disodium)

Cat. No.: HY-A0181BS Purity: 99.24%
Handling Instructions Technical Support

Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

For research use only. We do not sell to patients.

Adenosine monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> disodium Chemical Structure

Adenosine monophosphate-13C10,15N5 disodium Chemical Structure

Size Price Stock Quantity
Solvent
1 mg (100 mM in 25.19 μL Tris HCl/H2O buffer) In-stock

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Description

Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

406.08

Formula

13C10H1215N5Na2O7P

Unlabeled CAS
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[13C@@H]1[13C@H](O)[13C@@H]([13CH2]OP(O[Na])(O[Na])=O)O[13C@H]1[15N]2[13CH]=[15N][13C]3=[13C]2[15N]=[13CH][15N]=[13C]3[15NH2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, protect from light, 2 years

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (307.82 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4626 mL 12.3128 mL 24.6257 mL
5 mM 0.4925 mL 2.4626 mL 4.9251 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.24%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4626 mL 12.3128 mL 24.6257 mL 61.5642 mL
5 mM 0.4925 mL 2.4626 mL 4.9251 mL 12.3128 mL
10 mM 0.2463 mL 1.2313 mL 2.4626 mL 6.1564 mL
15 mM 0.1642 mL 0.8209 mL 1.6417 mL 4.1043 mL
20 mM 0.1231 mL 0.6156 mL 1.2313 mL 3.0782 mL
25 mM 0.0985 mL 0.4925 mL 0.9850 mL 2.4626 mL
30 mM 0.0821 mL 0.4104 mL 0.8209 mL 2.0521 mL
40 mM 0.0616 mL 0.3078 mL 0.6156 mL 1.5391 mL
50 mM 0.0493 mL 0.2463 mL 0.4925 mL 1.2313 mL
60 mM 0.0410 mL 0.2052 mL 0.4104 mL 1.0261 mL
80 mM 0.0308 mL 0.1539 mL 0.3078 mL 0.7696 mL
100 mM 0.0246 mL 0.1231 mL 0.2463 mL 0.6156 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Adenosine monophosphate-13C10,15N5 disodium
Cat. No.:
HY-A0181BS
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