2. Others Metabolic Enzyme/Protease GPCR/G Protein
  3. CaSR Endogenous Metabolite Isotope-Labeled Compounds
  4. Cinacalcet-d4 hydrochloride

Cinacalcet-d4 hydrochloride  (Synonyms: AMG-073-d4 hydrochloride)

Cat. No.: HY-W653978
Handling Instructions Technical Support

Cinacalcet-d4 (AMG-073-d4) hydrochlorideis deuterium labeled Cinacalcet (hydrochloride). Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.

For research use only. We do not sell to patients.

Cinacalcet-d<sub>4</sub> hydrochloride Chemical Structure

Cinacalcet-d4 hydrochloride Chemical Structure

CAS No. : 2514927-75-2

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2.5 mg Get quote 2-4 weeks 2-4 weeks 2-4 weeks
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Cinacalcet-d4 hydrochloride Related Antibodies

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Description

Cinacalcet-d4 (AMG-073-d4) hydrochlorideis deuterium labeled Cinacalcet (hydrochloride). Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment[1].

Molecular Weight

397.90

Formula

C22H19D4ClF3N
CAS No.
Unlabeled CAS
SMILES

C[C@H](C1=C2C=CC=CC2=CC=C1)NC([2H])(C([2H])(CC3=CC=CC(C(F)(F)F)=C3)[2H])[2H].Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (125.66 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1 mg/mL (2.51 mM; ultrasonic and warming and heat to 60°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5132 mL 12.5660 mL 25.1319 mL
5 mM 0.5026 mL 2.5132 mL 5.0264 mL
View the Complete Stock Solution Preparation Table

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.5132 mL 12.5660 mL 25.1319 mL 62.8299 mL
DMSO 5 mM 0.5026 mL 2.5132 mL 5.0264 mL 12.5660 mL
10 mM 0.2513 mL 1.2566 mL 2.5132 mL 6.2830 mL
15 mM 0.1675 mL 0.8377 mL 1.6755 mL 4.1887 mL
20 mM 0.1257 mL 0.6283 mL 1.2566 mL 3.1415 mL
25 mM 0.1005 mL 0.5026 mL 1.0053 mL 2.5132 mL
30 mM 0.0838 mL 0.4189 mL 0.8377 mL 2.0943 mL
40 mM 0.0628 mL 0.3141 mL 0.6283 mL 1.5707 mL
50 mM 0.0503 mL 0.2513 mL 0.5026 mL 1.2566 mL
60 mM 0.0419 mL 0.2094 mL 0.4189 mL 1.0472 mL
80 mM 0.0314 mL 0.1571 mL 0.3141 mL 0.7854 mL
100 mM 0.0251 mL 0.1257 mL 0.2513 mL 0.6283 mL
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Cinacalcet-d4 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cinacalcet-d42514927-75-2AMG-073-d4CaSREndogenous MetaboliteIsotope-Labeled CompoundsCalcium-sensing receptorInhibitorinhibitorinhibit

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