Search Result

Pathways Recommended:	Immunology/Inflammation

Results for "

Inflammation_Immunology

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (1) Apoptosis (3) Arenavirus (1) C-type Lectin-like Receptors (CTLRs) (2) CD28 (3) COX (6) DNA/RNA Synthesis (1) Epoxide Hydrolase (1) ERK (1) Fungal (1) HIV Protease (1) Integrin (2) Interleukin Related (4) Isotope-Labeled Compounds (1) MAPKAPK2 (MK2) (1) Opioid Receptor (1) Protease Activated Receptor (PAR) (3) Reference Standards (4) SARS-CoV (1) TNF Receptor (1) Toll-like Receptor (TLR) (1) Transmembrane Glycoprotein (3)
By Research Areas:	Cancer (19) Cardiovascular Disease (4) Infection (6) Inflammation/Immunology (29) Metabolic Disease (17) Neurological Disease (5)

By Targets:

Angiotensin-converting Enzyme (ACE) (1)

Apoptosis (3)

Arenavirus (1)

C-type Lectin-like Receptors (CTLRs) (2)

CD28 (3)

COX (6)

DNA/RNA Synthesis (1)

Epoxide Hydrolase (1)

ERK (1)

Fungal (1)

HIV Protease (1)

Integrin (2)

Interleukin Related (4)

Isotope-Labeled Compounds (1)

MAPKAPK2 (MK2) (1)

Opioid Receptor (1)

Protease Activated Receptor (PAR) (3)

Reference Standards (4)

SARS-CoV (1)

TNF Receptor (1)

Toll-like Receptor (TLR) (1)

Transmembrane Glycoprotein (3)

By Research Areas:

Cancer (19)

Cardiovascular Disease (4)

Infection (6)

Inflammation/Immunology (29)

Metabolic Disease (17)

Neurological Disease (5)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148016

I-287	Protease Activated Receptor (PAR) ERK	Inflammation/Immunology
I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gα_q and Gα_12/13 activity and their downstream effectors. I-287 reduces Complete Freund's adjuvant (HY-153808)-induced inflammation in mice and can be used for inflammation/immunology research .

HY-B0227

Ketoprofen Maximum Cited Publications 7 Publications Verification RP-19583	COX	Metabolic Disease Inflammation/Immunology Cancer
Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC₅₀ values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-P1263

tcY-NH2 1 Publications Verification (trans-Cinnamoyl)-YPGKF-NH2	Protease Activated Receptor (PAR)	Metabolic Disease Inflammation/Immunology
tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH₂-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .

HY-P1263A

tcY-NH2 TFA 1 Publications Verification (trans-Cinnamoyl)-YPGKF-NH2 TFA	Protease Activated Receptor (PAR)	Metabolic Disease Inflammation/Immunology
tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH₂-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .

HY-N1403

Tigogenin	Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Tigogenin is a steroidal sapogenins. Tigogenin can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin can inhibit cells proliferation and induce apoptosis. Tigogenin can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .

HY-155029

sEH inhibitor-16	Epoxide Hydrolase	Inflammation/Immunology
sEH inhibitor-16 is a soluble epoxide hydrolase (sEH) inhibitors with an IC₅₀ of 2 nM. sEH inhibitor-16 reduces the inflammatory damage in Cerulein (HY-A0190)-induced acute pancreatitis (AP) in mice and can be used for inflammation/immunology research .

HY-147283

MK2-IN-4	MAPKAPK2 (MK2)	Inflammation/Immunology Cancer
MK2-IN-4 is a MAPKAPK2 (MK2) inhibitor with an IC₅₀ value of 45 nM. MK2-IN-4 can be used in the research of cancer, inflammation, immunology .

HY-167630

Ketoprofen sodium 19583 RP-Na	COX	Metabolic Disease Inflammation/Immunology Cancer
Ketoprofen (RP-19583) sodium is a non-steroidal anti-inflammatory agent. Ketoprofen sodium can inhibit the activity of Cyclooxygenase with IC₅₀ values of 2 nM (COX-1) and 26 nM (COX-2). Ketoprofen is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-B0227A

Ketoprofen (lysinate) RP-19583 (lysinate)	COX	Metabolic Disease Inflammation/Immunology Cancer
Ketoprofen (RP-19583) lysinate is a non-steroidal anti-inflammatory agent. Ketoprofen lysinate can inhibit the activity of cyclooxygenase with IC₅₀ values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-B0227R

Ketoprofen (Standard) RP-19583 (Standard)	Reference Standards COX	Metabolic Disease Inflammation/Immunology Cancer
Ketoprofen (Standard) is the analytical standard of Ketoprofen. This product is intended for research and analytical applications. Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC₅₀ values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-B0227AR

Ketoprofen (lysinate) (Standard) RP-19583 (lysinate) (Standard)	Reference Standards COX	Metabolic Disease Inflammation/Immunology Cancer
Ketoprofen (lysinate) (Standard) is the analytical standard of Ketoprofen (lysinate). This product is intended for research and analytical applications. Ketoprofen (RP-19583) lysinate is a non-steroidal anti-inflammatory agent. Ketoprofen lysinate can inhibit the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-110252

Salvinorin B	Opioid Receptor	Neurological Disease Inflammation/Immunology
Salvinorin B is a selective and brain-penetrant kappa opioid receptor (KOPr) agonist with an EC₅₀ of 248 nM and K_i of 2.95 μM. Salvinorin B activates downstream signaling pathways by binding to KOPr, inhibits pain transmission and reduces inflammatory response. Salvinorin B can be used for the researches of inflammation, immunology and neurological disease, such as neuropathic pain, multiple sclerosis and anxiety .

HY-B0227S3

Ketoprofen-13C6 RP-19583-¹³C₆	Isotope-Labeled Compounds COX	Metabolic Disease Inflammation/Immunology Cancer
Ketoprofen- ¹³C₆ (RP-19583- ¹³C₆) is ¹³C labeled Ketoprofen. Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC₅₀ values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-N1403R

Tigogenin (Standard)	Reference Standards Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Tigogenin (Standard) is a steroidal sapogenins. Tigogenin (Standard) can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin (Standard) can inhibit cells proliferation and induce apoptosis. Tigogenin (Standard) can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .

HY-N6773R

Cytochalasin A (Standard)	Reference Standards HIV Protease Fungal	Infection
Ketoprofen (lysinate) (Standard) is the analytical standard of Ketoprofen (lysinate). This product is intended for research and analytical applications. Ketoprofen (RP-19583) lysinate is a non-steroidal anti-inflammatory agent. Ketoprofen lysinate can inhibit the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .

HY-P990295

Anti-Mouse CD103 Antibody (M290)	Integrin	Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse CD103 Antibody (M290) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD103. Anti-Mouse CD103 Antibody (M290) can neutralize CD103. Anti-Mouse CD103 Antibody (M290) can be used for the researches of cancer, inflammation, immunology and metabolic disease, such as B16.gp33 tumor, colitis and diabetes .

HY-138113

Pyrrothiogatain	DNA/RNA Synthesis Interleukin Related TNF Receptor Angiotensin-converting Enzyme (ACE) SARS-CoV	Infection Inflammation/Immunology Cancer
Pyrrothiogatain is a transcription factor GATA3 inhibitor with an IC₅₀ of 54.7 μM. Pyrrothiogatain inhibits the DNA-binding activity of GATA3 and inhibits the T helper 2 (Th2) cell differentiation and expression of Th2 cytokines. Pyrrothiogatain shows anti-infection effect by inhibiting ACE2 expression. Pyrrothiogatain can be used for the researches of inflammation, immunology, infection and cancer, such as colon cancer and SARS-CoV-2 infection .

HY-P990819

Anti-Rat CD28 Antibody (JJ316)	CD28	Neurological Disease Inflammation/Immunology
Anti-Rat CD28 Antibody (JJ316) is a mouse-derived agonistic IgG1 κ type antibody, targeting to rat CD28. Anti-Rat CD28 Antibody (JJ316) can induce T cell proliferation. Anti-Rat CD28 Antibody (JJ316) can be used for the researches of inflammation, immunology and neurological disease, such as experimental autoimmune encephalomyelitis (EAE) and graft-versus-host disease (GvHD) .

HY-P990793

Anti-Mouse CD28 Antibody (D665)	CD28	Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD28 Antibody (D665) is a mouse-derived agonistic IgG1 κ type antibody, targeting to mouse CD28. Anti-Mouse CD28 Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for the researches of neurological disease, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD) .

HY-175533

TLR2 antagonist-1	Toll-like Receptor (TLR)	Neurological Disease Inflammation/Immunology
TLR2 antagonist-1 is a selective Toll-like receptor 2 (TLR2) antagonist. TLR2 antagonist-1 can effectively inhibit excessive TLR2 activation (IC₅₀ = 11.41 μM) and the production of inflammatory factors. TLR2 antagonist-1 has metabolic stability with a half-life (T_1/2) of 16.67 min in mouse liver microsomes. TLR2 antagonist-1 can be used for the researches of inflammation, immunology, and neurological disease .

HY-P990262

Anti-Mouse CD8 Antibody (HB-129)	Transmembrane Glycoprotein	Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse CD8 Antibody (HB-129) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse CD8. Anti-Mouse CD8 Antibody (HB-129) can deplete CD8 ⁺ T cells. Anti-Mouse CD8 Antibody (HB-129) can be used for the researches of cancer, inflammation, immunology and metabolic disease, such as P815 tumor, experimental autoimmune thyroiditis (EAT) and graft versus host disease (GVHD) .

HY-P990284

Anti-Mouse CD205 Antibody (NLDC-145)	C-type Lectin-like Receptors (CTLRs)	Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse CD205 Antibody (NLDC-145) is a rat-derived IgG2aκ type antibody inhibitor, targeting to mouse CD205. Anti-Mouse CD205 Antibody (NLDC-145) reacts with CD205 also known as DEC-205. Anti-Mouse CD205 Antibody (NLDC-145) can be used for the researches of cancer, inflammation, immunology and metabolic disease, such as colitis, D2F2/E2 tumor and diabetes .

HY-P99120

Anti-Mouse CD11a Antibody (FD441.8)	Integrin	Inflammation/Immunology Cancer
Anti-Mouse CD11a Antibody (FD441.8) is an anti-mouse CD11a IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD11a Antibody (FD441.8) can neutralize CD11a also known as LFA-1α (lymphocyte function-associated antigen 1 alpha). Anti-Mouse CD11a Antibody (FD441.8) can be used for the researches of inflammation, immunology and cancer, such as transplant and leukemia .

HY-P990225

Anti-Mouse IL-12 p40 Antibody (C17.8)	Interleukin Related	Metabolic Disease Inflammation/Immunology
Anti-Mouse IL-12 p40 Antibody (C17.8) is a rat-derived anti-mouse IL-12 p40 IgG2a κ type antibody inhibitor. Anti-Mouse IL-12 p40 Antibody (C17.8) binds p40 subunit of IL-12. Anti-Mouse IL-12 p40 Antibody (C17.8) can be used for the researches of inflammation, immunology and metabolic disease, such as diabetes and arthritis .

HY-P990178

Anti-Mouse NKG2D/CD314 Antibody (CX5)	C-type Lectin-like Receptors (CTLRs)	Infection Others Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse NKG2D/CD314 Antibody (CX5) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse NKG2D/CD314. Anti-Mouse NKG2D/CD314 Antibody (CX5) reduces cytotoxicity of natural killer cells. Anti-Mouse NKG2D/CD314 Antibody (CX5) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as colitis and diabetes .

HY-P990166

Anti-Mouse PSGL-1/CD162 Antibody (4RA10)	Apoptosis Transmembrane Glycoprotein Arenavirus	Infection Inflammation/Immunology
Anti-Mouse PSGL-1/CD162 Antibody (4RA10) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse PSGL-1/CD162. Anti-Mouse PSGL-1/CD162 Antibody (4RA10) blocks PSGL signaling and inhibits leukocyte rolling. Anti-Mouse PSGL-1/CD162 Antibody (4RA10) can be used for the researches of inflammation, immunology and infection, such as pneumonia and lymphocytic choriomeningitis virus infection .

HY-P99123A

Anti-Mouse CD28 (LALA-PG) Antibody (D665)	CD28	Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD28 (LALA-PG) Antibody (D665) is an anti-mouse CD28 IgG2a monoclonal antibody. Anti-Mouse CD28 (LALA-PG) Antibody (D665) is a chimeric antibody of the original D665 antibody (HY-P990793). Anti-Mouse CD28 (LALA-PG) Antibody (D665) contains the LALA-PG mutation region. Anti-Mouse CD28 Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for research on neurological conditions, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD).

HY-P990822

Anti-Mouse TIM-1/CD365 Antibody (3D10)	Transmembrane Glycoprotein	Cardiovascular Disease Inflammation/Immunology
Anti-Mouse TIM-1/CD365 Antibody (3D10) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3D10) can block mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. Anti-Mouse TIM-1/CD365 Antibody (3D10) can be used for the researches of inflammation, immunology and cardiovascular disease, such as graft-versus-host disease (GVHD), airway inflammation and atherosclerosis .

HY-P990209

Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) 1 Publications Verification	Interleukin Related	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .

HY-P990808

Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1)	Interleukin Related	Infection Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) is a rat-derived IgG2b κ type antibody inhibito, targeting to mouse CD122/IL-2Rβ. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can block IL-2 and IL-15. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can deplete natural killer (NK) cells and NKT cells. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as melanoma, experimental autoimmune encephalomyelitis (EAE) and diabetes .

Cat. No.	Product Name	Target	Research Area