2. Recombinant Proteins
  3. Cytokines and Growth Factors CD Antigens
  4. Interleukin & Receptors NK Cell CD Proteins
  5. IL-2 Receptor IL-2R beta/CD122
  6. IL-2R beta/CD122
  7. IL-2R beta/CD122 Protein, Mouse (HEK293, hFc)

IL-2R beta/CD122 Protein, Mouse (HEK293, hFc)

Cat. No.: HY-P704711
Handling Instructions Technical Support

IL-2R beta/CD122 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived IL-2R beta/CD122 protein, expressed by HEK293, with C-hFc tag.

For research use only. We do not sell to patients.

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50 μg Ask For Quote & Lead Time

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Description

IL-2R beta/CD122 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived IL-2R beta/CD122 protein, expressed by HEK293, with C-hFc tag.
Background

IL-2R beta serves as a receptor subunit for interleukin-2, mediating receptor endocytosis and transducing IL2's mitogenic signals. It likely collaborates with IL15RA to facilitate IL15-induced neutrophil phagocytosis (By similarity).
Species

Mouse
Source

HEK293
Tag

C-hFc
Accession

P16297 (A27-E240)
Gene ID

16185
Molecular Construction
N-term
IL-2Rβ (A27-E240)
Accession # P16297
hFc
C-term
Synonyms
Il2rbInterleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; p70-75; CD antigen CD122
Predicted Molecular Mass
51.5 kDa.
Molecular Weight

Approximately 65-80 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IL-2R beta/CD122 Protein, Mouse (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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