1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Drug Metabolite
  3. Tazarotenic acid-d8

Tazarotenic acid-d8 (AGN 190299-d8) is the deuterium labeled Tazarotenic acid (HY-101108). Tazarotenic acid is the metabolite of Tazarotene (HY-15388).

For research use only. We do not sell to patients.

Tazarotenic acid-d<sub>8</sub> Chemical Structure

Tazarotenic acid-d8 Chemical Structure

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Description

Tazarotenic acid-d8 (AGN 190299-d8) is the deuterium labeled Tazarotenic acid (HY-101108). Tazarotenic acid is the metabolite of Tazarotene (HY-15388)[1].

Molecular Weight

331.46

Formula

C19H9D8NO2S

Unlabeled CAS
SMILES

OC(C1=CN=C(C#CC2=CC3=C(SCC([2H])(C3(C([2H])([2H])[2H])C([2H])([2H])[2H])[2H])C=C2)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (301.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0170 mL 15.0848 mL 30.1696 mL
5 mM 0.6034 mL 3.0170 mL 6.0339 mL
View the Complete Stock Solution Preparation Table
  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0170 mL 15.0848 mL 30.1696 mL 75.4239 mL
5 mM 0.6034 mL 3.0170 mL 6.0339 mL 15.0848 mL
10 mM 0.3017 mL 1.5085 mL 3.0170 mL 7.5424 mL
15 mM 0.2011 mL 1.0057 mL 2.0113 mL 5.0283 mL
20 mM 0.1508 mL 0.7542 mL 1.5085 mL 3.7712 mL
25 mM 0.1207 mL 0.6034 mL 1.2068 mL 3.0170 mL
30 mM 0.1006 mL 0.5028 mL 1.0057 mL 2.5141 mL
40 mM 0.0754 mL 0.3771 mL 0.7542 mL 1.8856 mL
50 mM 0.0603 mL 0.3017 mL 0.6034 mL 1.5085 mL
60 mM 0.0503 mL 0.2514 mL 0.5028 mL 1.2571 mL
80 mM 0.0377 mL 0.1886 mL 0.3771 mL 0.9428 mL
100 mM 0.0302 mL 0.1508 mL 0.3017 mL 0.7542 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tazarotenic acid-d8
Cat. No.:
HY-W742417
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