FITC-Labeled CD20/MS4A1 Protein, Human (HEK293, His, Nanodisc)

CD20/MS4A1 protein is a B lymphocyte membrane protein that plays a crucial regulatory role in cellular calcium influx, which is essential for the development, differentiation and activation of B lymphocytes. As part of a store-operated calcium (SOC) channel, it promotes calcium influx upon B cell receptor/BCR activation. FITC-Labeled CD20/MS4A1 Protein, Human (HEK293, His, Nanodisc) is the recombinant human-derived FITC-Labeled CD20/MS4A1 protein, expressed by HEK293, with C-His labeled tag.

The CD20/MS4A1 protein, a B-lymphocyte-specific membrane protein, plays a crucial role in regulating cellular calcium influx essential for the development, differentiation, and activation of B-lymphocytes. It functions as a component of the store-operated calcium (SOC) channel, promoting calcium influx upon activation by the B-cell receptor/BCR. CD20/MS4A1 forms homotetramers, contributing to its structural organization and functional role in calcium signaling. Notably, it interacts with both the heavy and light chains of cell surface IgM, the antigen-binding components of the BCR, highlighting its involvement in the B-cell receptor complex and underscoring its significance in B-cell activation and immune responses.

Human

HEK293

C-His

P11836 (M1-P297)

931

Full Length

Approximately 26 kDa & 40 kDa & 70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Greater than 85% as determined by reducing SDS-PAGE.

Solution.

Supplied as 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, pH7.5 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt, protect from light. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.