2. Recombinant Proteins
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins
  5. TNF Receptor Superfamily CD40 GITR/CD357
  6. CD40 Protein, Rabbit (HEK293, His)

TNFR5/CD40, governs cellular responses to TNF, impacting inflammation, apoptosis, and immune processes. Its functions vary based on interactions with TNF ligands and other proteins in different cellular contexts. CD40 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived CD40 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD40 Protein, Rabbit (HEK293, His) is 173 a.a., with molecular weight of 28-35 kDa.

For research use only. We do not sell to patients.

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Description

TNFR5/CD40, governs cellular responses to TNF, impacting inflammation, apoptosis, and immune processes. Its functions vary based on interactions with TNF ligands and other proteins in different cellular contexts. CD40 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived CD40 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD40 Protein, Rabbit (HEK293, His) is 173 a.a., with molecular weight of 28-35 kDa.
Background

TNFR5/CD40, also known as Tumor Necrosis Factor Receptor Superfamily Member 5, is a protein belonging to the tumor necrosis factor receptor superfamily. TNFR5 is involved in cellular responses to tumor necrosis factor (TNF) and contributes to various physiological processes, including inflammation, apoptosis, and immune regulation. The specific functions and signaling pathways mediated by TNFR5 depend on its interactions with TNF ligands and other associated proteins in different cellular contexts.
Species

Rabbit
Source

HEK293
Tag

C-His
Accession

G1SPC6 (E77-R249)
Gene ID
Molecular Construction
N-term
CD40 (E77-R249)
Accession # G1SPC6
His
C-term
Synonyms
CD40; Bp50; CDW40; MGC9013; TNFRSF5; p50
Molecular Weight

28-35 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CD40 Protein, Rabbit (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD40 Protein, Rabbit (HEK293, His)
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