2. Immunology/Inflammation
  3. CD3
  4. Gresonitamab

Gresonitamab  (Synonyms: AMG 910; Anti-Human CD3xClaudin18 2)

Cat. No.: HY-P99350 Purity: 99.12%
SDS
COA
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Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.

For research use only. We do not sell to patients.

CAS No. : 2413817-97-5

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Description

Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma[1].

Isotype

(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
Species

Human; Chimeric
In Vitro

Gresonitamab redirects tumor cell lysis to kill tumor cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gresonitamab Related Antibodies
Clinical Trial
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

106 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Gresonitamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • (scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
Biological Activity
  • Immobilized Gresonitamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 3.97 ng/mL.
Purity & Documentation

Purity: 99.12%

SDS (251 KB)

COA (232 KB) SDS-PAGE (566 KB) SEC-HPLC (678 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Gresonitamab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gresonitamab2413817-97-5AMG 910 Anti-Human CD3xClaudin18 2AMG910AMG-910CD3Cluster of differentiation 3BiTEHLEantibodyadenocarcinomaInhibitorinhibitorinhibit

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