1,10-Decanediol-d₂₀

Cat. No.: HY-W016773S: Data Sheet Handling Instructions
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1,10-Decanediol-d₂₀ is the deuterium labeled 1,10-Decanediol. 1,10-Decanediol is a diol compound that can react with α-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism. can be used as a surfactant/stabilizer in the synthesis of nanomaterials.

For research use only. We do not sell to patients.

1,10-Decanediol-d₂₀ Chemical Structure

CAS No. : 347841-78-5

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1 mg		Get quote	Estimated Time of Arrival: December 31

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Description	1,10-Decanediol-d₂₀ is the deuterium labeled 1,10-Decanediol^[1]. 1,10-Decanediol is a diol compound that can react with α-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism. can be used as a surfactant/stabilizer in the synthesis of nanomaterials^[1]^[2].
Application	1. This compound can be used as a tracer. 2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 1,10-Decanediol-d₂₀ Related Antibodies
Molecular Weight	194.40
Formula	C₁₀H₂D₂₀O₂
CAS No.	347841-78-5
Unlabeled CAS	112-47-0
SMILES	OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Mangal JL, et al. Metabolite releasing polymers control dendritic cell function by modulating their energy metabolism. J Mater Chem B. 2020 Jun 24;8(24):5195-5203. [Content Brief] [2]. Harris R A, et al. Molecular dynamics study on iron oxide nanoparticles stabilised with Sebacic Acid and 1, 10-Decanediol surfactants[J]. Journal of Molecular Structure, 2013, 1048: 18-26.