CD105 Antibody (YA3837)

Cat. No.: HY-P84140: Data Sheet User Guide for Antibodies
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CD105 Antibody (YA3837) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD105. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	CD105 Antibody (YA3837) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD105. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.
Background	CD105 is a vascular endothelium glycoprotein that plays a crucial role in angiogenesis regulation. It is essential for the normal structure and integrity of adult vasculature and regulates the migration of vascular endothelial cells. CD105 may mediate endothelial cell shape changes in response to blood flow, facilitating vascular remodeling and the establishment of normal vascular morphology. Additionally, it may critically contribute to the binding of endothelial cells to integrins and/or other RGD receptors. Acting as a TGF-beta coreceptor, CD105 participates in the TGF-beta/BMP signaling cascade, ultimately activating SMAD transcription factors. It is required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling via SMAD3. By similarity, CD105 is involved in extraembryonic angiogenesis and embryonic heart development.
Gene ID	2022 [NCBI]
SwissProt ID	P17813
Synonyms	ENG; END; ORW; HHT1; ORW1; CD105; FLJ41744
Molecular Weight	Predicted band size: 71 kDa; Observed band size: 71 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human
Dilution Ratio	IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000
Application	IHC-P, ICC/IF, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human CD105 expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

CD105 Antibody (YA3837) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD105 Antibody (YA3837)

Biological Activity

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CD105 Antibody (YA3837) Related Classifications

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