CD68 Antibody (YA7191)

CD68 Antibody (YA7191) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD68.

CD68: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

affinity purified

Unmodified

Primary Antibody; Recombinant Mouse Monoclonal Antibody

Monoclonal, Recombinant

Mouse

Human

IHC-P: 1:200-1:4,000; IF-Cell: 1:100; FC: 1:500-1:1,000; mIHC: 1:2,000; IF-Tissue: 1:50-1:800

IHC-P, ICC/IF, FC, IF-Tissue, mIHC

Human spleen tissue, human diffuse large B-cell lymphoma tissue, human tonsil tissue, human liver tissue, THP-1

Liquid

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Recombinant protein within Human CD68 aa 1-354.