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  4. PDGF R beta Protein, Cynomolgus (HEK293, His)

PDGF R beta Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P703816
Handling Instructions Technical Support

PDGF R beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PDGF R beta protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

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Description

PDGF R beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PDGF R beta protein, expressed by HEK293, with C-His tag.
Background

PDGF R beta, a tyrosine-protein kinase, serves as a cell-surface receptor for homodimeric PDGFB and PDGFD, as well as heterodimers formed by PDGFA and PDGFB. This receptor plays a crucial role in the intricate regulation of embryonic development, overseeing processes such as cell proliferation, survival, differentiation, chemotaxis, and migration. Particularly vital in blood vessel development, PDGF R beta facilitates the proliferation, migration, and recruitment of pericytes and smooth muscle cells to endothelial cells, contributing significantly to the formation and maintenance of blood vessels.
Species

Cynomolgus
Source

HEK293
Tag

C-8*His
Accession

A0A2K5TUS0 (L33-K531)
Gene ID

/
Protein Length

Extracellular Domain
Synonyms
Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Predicted Molecular Mass
57.5 kDa
Molecular Weight

Approximately 75-105 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PDGF R beta Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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