1. Others Metabolic Enzyme/Protease
  2. Aldose Reductase Isotope-Labeled Compounds
  3. Epalrestat-d5

Epalrestat-d5 is deuterium labeled Epalrestat. Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy.

For research use only. We do not sell to patients.

Epalrestat-d<sub>5</sub> Chemical Structure

Epalrestat-d5 Chemical Structure

CAS No. : 2755644-33-6

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5 mg In-stock
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Description

Epalrestat-d5 is deuterium labeled Epalrestat. Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy[1][2][3][4].

Molecular Weight

324.43

Formula

C15H8D5NO3S2

CAS No.
Unlabeled CAS
SMILES

O=C(N1CC(O)=O)/C(SC1=S)=C/C(C)=C/C2=C(C([2H])=C(C([2H])=C2[2H])[2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (61.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0823 mL 15.4116 mL 30.8233 mL
5 mM 0.6165 mL 3.0823 mL 6.1647 mL
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0823 mL 15.4116 mL 30.8233 mL 77.0582 mL
5 mM 0.6165 mL 3.0823 mL 6.1647 mL 15.4116 mL
10 mM 0.3082 mL 1.5412 mL 3.0823 mL 7.7058 mL
15 mM 0.2055 mL 1.0274 mL 2.0549 mL 5.1372 mL
20 mM 0.1541 mL 0.7706 mL 1.5412 mL 3.8529 mL
25 mM 0.1233 mL 0.6165 mL 1.2329 mL 3.0823 mL
30 mM 0.1027 mL 0.5137 mL 1.0274 mL 2.5686 mL
40 mM 0.0771 mL 0.3853 mL 0.7706 mL 1.9265 mL
50 mM 0.0616 mL 0.3082 mL 0.6165 mL 1.5412 mL
60 mM 0.0514 mL 0.2569 mL 0.5137 mL 1.2843 mL
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Epalrestat-d5
Cat. No.:
HY-W653944
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