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  5. CD20/MS4A1 Protein-VLP, Cynomolgus (297a.a, HEK293, His)

CD20/MS4A1 Protein-VLP, Cynomolgus (297a.a, HEK293, His)

Cat. No.: HY-P78579
Handling Instructions Technical Support

CD20/MS4A1 Protein-VLP, Cynomolgus (297a.a, HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

For research use only. We do not sell to patients.

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Description

CD20/MS4A1 Protein-VLP, Cynomolgus (297a.a, HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

Background

The CD20/MS4A1 Protein-VLP, Cynomolgus, is a member of the MS4A family, playing a significant role in immune system modulation. As part of this family, CD20/MS4A1 contributes to the regulation of B-cell activation and differentiation. The protein, in the form of virus-like particles (VLPs), holds promise for applications in immunotherapy and vaccine development, particularly in the context of B-cell-related disorders. By belonging to the MS4A family, CD20/MS4A1 Protein-VLP, Cynomolgus, highlights its importance in understanding and potentially manipulating immune responses, offering avenues for further research and therapeutic interventions.

Species

Cynomolgus

Source

HEK293

Tag

C-10*His

Accession

M4ZHZ6 (M1-P297)

Gene ID
Molecular Construction
N-term
CD20 (M1-P297)
Accession # M4ZHZ6
10*His
C-term
Protein Length

Full Length

Synonyms
MS4A1; CD20; MS4A-1
AA Sequence

MTTPRNSVNGTFPAEPMKGPIAMQPGPKPLLRRMSSLVGPTQSFFMRESKALGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRVHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWRRTCSRPKSSVVLLSAEEKKEQVIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Predicted Molecular Mass
34.4 kDa
Purity

Greater than 80% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CD20/MS4A1 Protein-VLP, Cynomolgus (297a.a, HEK293, His)
Cat. No.:
HY-P78579
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