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  4. CD195/CCR5 Antibody (YA5578)

CD195/CCR5 Antibody (YA5578)

Cat. No.: HY-P85886
User Guide for Antibodies Technical Support

CD195/CCR5 Antibody (YA5578) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD195/CCR5. It can be applicated for FC, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CD195/CCR5 Antibody (YA5578) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD195/CCR5. It can be applicated for FC, ELISA assays, in the background of human.

Background

CD195 is a receptor for inflammatory CC-chemokines, including CCL3/MIP-1-alpha, CCL4/MIP-1-beta, and RANTES, and transduces signals by increasing intracellular calcium ion levels. It may play a role in controlling granulocytic lineage proliferation or differentiation and participates in T-lymphocyte migration to infection sites by acting as a chemotactic receptor. Additionally, CD195 serves as a coreceptor (with CD4 as the primary receptor) for human immunodeficiency virus-1/HIV-1 during microbial infection.

Gene ID
SwissProt ID
Synonyms
C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; CHEMR13; HIV-1 fusion coreceptor; CD antigen CD195;
Molecular Weight

Observed band size: 40 kDa

Purity

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Recombinant Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

Dilution Ratio

ELISA: 1:5000-100000; FC: 1-2μg/Test

Application

FC, ELISA

Appearance

Liquid

Formulation

Supplied in Phosphate-buffered solution

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Immunogen

Purified recombinant human CCR5

Documentation

CD195/CCR5 Antibody (YA5578) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CD195/CCR5 Antibody (YA5578)
Cat. No.:
HY-P85886
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