2. Others Neuronal Signaling Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds TRP Channel Endogenous Metabolite Calcium Channel
  4. Farnesyl pyrophosphate-d2 triammonium

Farnesyl pyrophosphate-d2 triammonium  (Synonyms: Farnesyl diphosphate-d2 triammonium)

Cat. No.: HY-113037CS Purity: 95.78%
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Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

For research use only. We do not sell to patients.

Farnesyl pyrophosphate-d<sub>2</sub> triammonium

Farnesyl pyrophosphate-d2 triammonium Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Farnesyl pyrophosphate-d2 triammonium:

Farnesyl pyrophosphate-d2 triammonium Related Antibodies

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TRPC TRPM TRPV TRPA TRPML

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Farnesyl pyrophosphate-d2 triammonium Related Antibodies
Molecular Weight

435.43

Formula

C15H35D2N3O7P2
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O)OP(OC([2H])([2H])/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(O)=O.N.N.N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
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Farnesyl pyrophosphate-d2 triammonium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Farnesyl pyrophosphate-d2 triammoniumFarnesyl diphosphate-d2 triammoniumIsotope-Labeled CompoundsTRP ChannelEndogenous MetaboliteCalcium ChannelTransient receptor potential channelsCa2+ channelsCa channelsInhibitorinhibitorinhibit

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