Pirenzepine-d₁₁  (Synonyms: LS 519 free base-d₁₁; Pirenzepin-d₁₁; Gastrozepin-d₁₁)

Pirenzepine-d₁₁ (LS 519 (free base)-d₁₁; Pirenzepin-d₁₁; Gastrozepin-d₁₁) is the deuterium labeled Pirenzepine (HY-17037A). Pirenzepine (LS 519 free base) is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine shows anti-proliferative activity to cancer cells^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

362.47

C₁₉H₁₀D₁₁N₅O₂

28797-61-7

O=C(N(C1=C2C=CC=C1)C3=C(C=CC=N3)NC2=O)CN4C([2H])(C([2H])(N(C([2H])(C4([2H])[2H])[2H])C([2H])([2H])[2H])[2H])[2H]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.