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  2. In Vivo Antibodies
  3. Anti-Mouse CD200 Antibody (OX-90)

Anti-Mouse CD200 Antibody (OX-90) 

Cat. No.: HY-P990285 Purity: 95.00%
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Anti-Mouse CD200 Antibody (OX-90) is an anti-mouse CD200 IgG2a monoclonal antibody. Anti-Mouse CD200 Antibody (OX-90) can reduce immune cell infiltration and T cell function by blocking CD200. Anti-Mouse CD200 Antibody (OX-90) can be used for research on immunology.

For research use only. We do not sell to patients.

Anti-Mouse CD200 Antibody (OX-90)

Anti-Mouse CD200 Antibody (OX-90) Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

Anti-Mouse CD200 Antibody (OX-90) is an anti-mouse CD200 IgG2a monoclonal antibody. Anti-Mouse CD200 Antibody (OX-90) can reduce immune cell infiltration and T cell function by blocking CD200. Anti-Mouse CD200 Antibody (OX-90) can be used for research on immunology[1][2].

Isotype

Rat IgG2a kappa

Recommend Isotype Controls
IC50 & Target

CD200

In Vivo

Anti-Mouse CD200 Antibody (OX-90) (250 μg, i.p., once every 3 days, from day 7 to day 18) reduces immune cell infiltration and T cell function in tumor immune microenvironment (TIME) in C57BL/6 mice bearing Yumm1.7 tumors[1].
Anti-Mouse CD200 Antibody (OX-90) (200 μg, i.v., on day 3, 6, 9,12) can weaken the therapeutic effect of anti-PD-L1 mAb in female C57BL/6 mice bearing MC38 or EG7 tumors[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 5×105 Yumm1.7 cells injected C57BL/6 mice[1]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), once every 3 days, from day 7 to day 18
Result: Reduced immune cells in tumors and upregulated CCL8 expression.
Animal Model: 5×105 MC38 or EG7 cells injected female C57BL/6 mice (6-8 weeks)[2]
Dosage: 200 μg
Administration: Intravenous injection (i.v.), on day 3, 6, 9,12
Result: Weakened the therapeutic effect of anti-PD-L1 mAb.
Gene ID

17470  [NCBI]

Accession
Application

ELISA, FACS, Functional assay, Research in vivo

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse CD200 Antibody (OX-90)]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Anti-Mouse CD200 Antibody (OX-90) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-Mouse CD200 Antibody (OX-90)
Cat. No.:
HY-P990285
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