Digitoxigenin-21,23,23-d₃  (Synonyms: Cerberigenin-d₃; Echujetin-d₃)

Digitoxigenin-21,23,23-d₃ (Cerberigenin-d₃; Echujetin-d₃) is the deuterium labeled Digitoxigenin (HY-B2151). Digitoxigenin is a steroid derivative commonly found in various plants, especially the foxglove plant (Digitalis purpurea). Digitoxigenin has unique chemical properties that make it an important precursor for the synthesis of cardiac glycosides, a group of drugs used to improve heart failure and certain types of arrhythmias. It works by inhibiting the sodium potassium ATPase pump, thereby increasing the force and efficiency of cardiac contractions.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

377.53

C₂₃H₃₁D₃O₄

34212-04-9

143-62-4

[H][C@@]12CC[C@@]3(C[C@H](CC[C@@]3([C@]1(CC[C@]4([C@@]2(CC[C@@H]4C5=C(C(OC5([2H])[2H])=O)[2H])O)C)[H])C)O)[H]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.