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  5. Rat Anti-Mouse CD86 Antibody (FITC)(YA3447)

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447)

Cat. No.: HY-P83710M
COA
SDS
User Guide for Antibodies Technical Support

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) is a rat-derived and fluorescein isothiocyanate (FITC) IgG2a monoclonal antibody, targeting to CD86. It can be applicated for FC assays, in the background of mouse.

For research use only. We do not sell to patients.

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100 T In-stock
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) is a rat-derived and fluorescein isothiocyanate (FITC) IgG2a monoclonal antibody, targeting to CD86. It can be applicated for FC assays, in the background of mouse.
Background

Rat Anti-Mouse CD86 is an antibody targeting mouse CD86, a receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy within 24 hours after activation. Additionally, it regulates B-cell function and influences IgG(1) production levels. Upon CD40 engagement, it activates the NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation. by similar: This antibody can be used to study the role of CD86 in immune regulation and its signaling mechanisms.
Gene ID
SwissProt ID
Synonyms
T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1
Molecular Weight

Predicted band size: 38 kDa; Observed band size: 70 kDa
Purity

Affinity
Conjugation

FITC
Modification

Unmodified
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Rat
Reactivity

Mouse
Dilution Ratio

FC: 5μL per test for million cells or whole blood in 100 μL volume.
Application

FC
Appearance

Liquid
Formulation

Supplied in PBS with 0.05% Proclin300, 1% BSA.
Storage & Stability

Stored at 2-8°C for 1 year, protect from light, do not freeze.
Shipping

Shipping with blue ice.
Isotype

IgG2a
Immunogen

A synthesized peptide derived from Mouse CD86.
Database

Entrez Gene: 12524 Mouse

SwissProt: P42082 Mouse

Documentation
SDS (251 KB)

COA (190 KB)

User Guide for Antibodies (1077 KB)

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Rat Anti-Mouse CD86 Antibody (FITC)(YA3447)
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