2. Anti-infection Immunology/Inflammation
  3. EBV IFNAR
  4. LMP2A (426-434)

LMP2A (426-434) is a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope of Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A). LMP2A (426-434) can trigger an immune response in individuals expressing different HLA-A*02 subtypes (A*02:01, A*02:03, A*02:06 and A*02:07). LMP2A (426-434) can induce a strong IFN-γ secretion response, stimulating the production of a high proportion of CD8+ IFN-γ+ T cells. LMP2A (426-434) induces specific CTLs to effectively kill target cells expressing LMP2A. LMP2A (426-434) can be used to study EBV-related malignant tumors (such as Hodgkin's disease and nasopharyngeal carcinoma) .

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Custom Peptide Synthesis

LMP2A (426-434)

LMP2A (426-434) Chemical Structure

CAS No. : 152274-91-4

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LMP2A (426-434) Related Antibodies

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Description

LMP2A (426-434) is a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope of Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A). LMP2A (426-434) can trigger an immune response in individuals expressing different HLA-A*02 subtypes (A*02:01, A*02:03, A*02:06 and A*02:07). LMP2A (426-434) can induce a strong IFN-γ secretion response, stimulating the production of a high proportion of CD8+ IFN-γ+ T cells. LMP2A (426-434) induces specific CTLs to effectively kill target cells expressing LMP2A. LMP2A (426-434) can be used to study EBV-related malignant tumors (such as Hodgkin's disease and nasopharyngeal carcinoma) [1][2].

In Vitro

LMP2A (426-434) (20 μg/mL, 24 h) induces IFN-γ secreting cells at a frequency of 80.6 SFC/5×10⁴ CD8+ T cells[1].
LMP2A (426-434) (20 μg/mL, 2 weeks) stimulation significantly increased the proportion of CD8+IFN-γ+ cells[1].
LMP2A (426-434) (20 μg/mL, 4 h)-specific CTLs effectively kills peptide-pulsed T2 cells and 293T-LMP2A cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LMP2A (426-434) Related Antibodies
Molecular Weight

906.16

Formula

C39H71N9O11S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Leu-Gly-Gly-Leu-Leu-Thr-Met-Val
Sequence Shortening

CLGGLLTMV
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (110.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1036 mL 5.5178 mL 11.0356 mL
5 mM 0.2207 mL 1.1036 mL 2.2071 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Working solution concentration: mg/mL
Purity & Documentation

Purity: 96.09%

SDS (252 KB)

COA (244 KB) RP-HPLC (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1036 mL 5.5178 mL 11.0356 mL 27.5889 mL
5 mM 0.2207 mL 1.1036 mL 2.2071 mL 5.5178 mL
10 mM 0.1104 mL 0.5518 mL 1.1036 mL 2.7589 mL
15 mM 0.0736 mL 0.3679 mL 0.7357 mL 1.8393 mL
20 mM 0.0552 mL 0.2759 mL 0.5518 mL 1.3794 mL
25 mM 0.0441 mL 0.2207 mL 0.4414 mL 1.1036 mL
30 mM 0.0368 mL 0.1839 mL 0.3679 mL 0.9196 mL
40 mM 0.0276 mL 0.1379 mL 0.2759 mL 0.6897 mL
50 mM 0.0221 mL 0.1104 mL 0.2207 mL 0.5518 mL
60 mM 0.0184 mL 0.0920 mL 0.1839 mL 0.4598 mL
80 mM 0.0138 mL 0.0690 mL 0.1379 mL 0.3449 mL
100 mM 0.0110 mL 0.0552 mL 0.1104 mL 0.2759 mL
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LMP2A (426-434) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LMP2A (426-434)152274-91-4EBVIFNAREpstein-Barr VirusInterferon-α/β receptorInterferon-alpha/beta receptorEpstein-Barr viruslatent membrane protein 2Aepitopecytotoxic T lymphocyteInhibitorinhibitorinhibit

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