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  4. TCEP-d12 hydrochloride

TCEP-d12 hydrochloride  (Synonyms: Tris(2-​carboxyethyl)​phosphine hydrochloride-d12)

Cat. No.: HY-W700621
Handling Instructions Technical Support

TCEP-d12 (hydrochloride) (Tris(2-?carboxyethyl)?phosphine hydrochloride-d12) is deuterium labeled TCEP (hydrochloride). TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry.

For research use only. We do not sell to patients.

TCEP-d<sub>12</sub> hydrochloride Chemical Structure

TCEP-d12 hydrochloride Chemical Structure

CAS No. : 1189959-10-1

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Based on 1 publication(s) in Google Scholar

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TCEP-d12 hydrochloride Related Antibodies

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Description

TCEP-d12 (hydrochloride) (Tris(2-?carboxyethyl)?phosphine hydrochloride-d12) is deuterium labeled TCEP (hydrochloride). TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry[1][2][3][4][5].

Molecular Weight

298.72

Formula

C9H4D12ClO6P
CAS No.
Unlabeled CAS
SMILES

OC(C([2H])([2H])C([2H])([2H])P(C([2H])([2H])C([2H])([2H])C(O)=O)C([2H])([2H])C([2H])([2H])C(O)=O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (334.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 50 mg/mL (167.38 mM; ultrasonic and adjust pH to 7 with NaOH)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3476 mL 16.7381 mL 33.4762 mL
5 mM 0.6695 mL 3.3476 mL 6.6952 mL
View the Complete Stock Solution Preparation Table

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.3476 mL 16.7381 mL 33.4762 mL 83.6904 mL
5 mM 0.6695 mL 3.3476 mL 6.6952 mL 16.7381 mL
10 mM 0.3348 mL 1.6738 mL 3.3476 mL 8.3690 mL
15 mM 0.2232 mL 1.1159 mL 2.2317 mL 5.5794 mL
20 mM 0.1674 mL 0.8369 mL 1.6738 mL 4.1845 mL
25 mM 0.1339 mL 0.6695 mL 1.3390 mL 3.3476 mL
30 mM 0.1116 mL 0.5579 mL 1.1159 mL 2.7897 mL
40 mM 0.0837 mL 0.4185 mL 0.8369 mL 2.0923 mL
50 mM 0.0670 mL 0.3348 mL 0.6695 mL 1.6738 mL
60 mM 0.0558 mL 0.2790 mL 0.5579 mL 1.3948 mL
80 mM 0.0418 mL 0.2092 mL 0.4185 mL 1.0461 mL
100 mM 0.0335 mL 0.1674 mL 0.3348 mL 0.8369 mL
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TCEP-d12 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TCEP-d121189959-10-1Tris(2-​carboxyethyl)​phosphine hydrochloride-d12OthersIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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