2. Recombinant Proteins
  3. Others
  4. IL-18R alpha Protein, Cynomolgus (HEK293, His)

IL-18R alpha Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P703778
Handling Instructions Technical Support

IL-18R alpha Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-18R alpha protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

IL-18R alpha Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-18R alpha protein, expressed by HEK293, with C-His tag.
Background

IL-18R alpha is a component of the IL-18 receptor complex, responsible for binding the pro-inflammatory cytokine IL-18 but not IL-1A or IL-1B. It is involved in IL-18-mediated IFNG synthesis from T-helper 1 (Th1) cells and contributes to IL-18-induced cytokine production, either independently of SLC12A3 or as a complex with SLC12A3.
Species

Cynomolgus
Source

HEK293
Tag

C-8*His
Accession

A0A2K5V3J9 (C22-G329)
Protein Length

Extracellular Domain
Synonyms
Interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a
Predicted Molecular Mass
36.5 kDa
Molecular Weight

Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IL-18R alpha Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
IL-18R alpha Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P703778
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.