1. Recombinant Proteins
  2. Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. C-Type Lectin Domain Family 10 Member A/CD301
  6. CLEC10A/CD301 Protein, Mouse (HEK293, His)

The CLEC10A/CD301 protein is a receptor that recognizes terminal galactose and N-acetylgalactosamine units and is involved in a variety of biological processes.It may play a crucial role by promoting interactions between tumor-killing macrophages and tumor cells.CLEC10A/CD301 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

Size Price Stock Quantity
Free Sample   Apply now
20 μg In-stock
50 μg In-stock
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

The CLEC10A/CD301 protein is a receptor that recognizes terminal galactose and N-acetylgalactosamine units and is involved in a variety of biological processes.It may play a crucial role by promoting interactions between tumor-killing macrophages and tumor cells.CLEC10A/CD301 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with C-His labeled tag.

Background

CLEC10A/CD301 Protein is a receptor that specifically recognizes terminal galactose and N-acetylgalactosamine units, suggesting its involvement in various biological processes. It may play a crucial role in facilitating the interaction between tumoricidal macrophages and tumor cells. Additionally, CLEC10A/CD301 Protein has been implicated in the recruitment of inflammatory monocytes to adipose tissue during diet-induced obesity. It forms homooligomers and interacts with SIGLEC1, potentially acting as a counter-receptor for CLEC10A/CD301 Protein in lymph nodes.

Species

Mouse

Source

HEK293

Tag

C-8*His

Accession

P49300 (Q57-S304)

Gene ID
Molecular Construction
N-term
CLEC10A (Q57-S304)
Accession # P49300
8*His
C-term
Protein Length

Extracellular Domain

Synonyms
C-type lectin domain family 10 member A; CD301; CLEC10A; CLECSF13; CLECSF14; HML
Molecular Weight

38-45 kDa.

Glycosylation
Yes
Purity

Greater than 95% as determined by Tris-Bis PAGE under reduced condition.

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
CLEC10A/CD301 Protein, Mouse (HEK293, His)
Cat. No.:
HY-P76266
Quantity:
MCE Japan Authorized Agent: