Anti-Mouse E-selectin/CD62E Antibody (9A9) 

Anti-Mouse E-selectin/CD62E Antibody (9A9) is an anti-mouse E-selectin/CD62E IgG2b monoclonal antibody. Anti-Mouse E-selectin/CD62E Antibody (9A9) has an inhibitory effect on cancer cell colonization. Anti-Mouse E-selectin/CD62E Antibody (9A9) can be used for researches on inflammation conditions and cancer such as acute microvascular inflammation and breast cancer^[1][2].

Rat IgG1 kappa

Rat IgG1 kappa, Isotype Control

Mouse

E-selectin/CD62E

Anti-Mouse E-selectin/CD62E Antibody (9A9) (30 μg, single dose) significantly increases the rolling velocities of white blood cells in C57BL/6 mice with an acute microvascular inflammation model^[1].
Anti-Mouse E-selectin/CD62E Antibody (9A9) (10 mg/kg, i.v., single dose) significantly reduces early lung colonization of cancer cells in C57BL/6 mice bearing E0771 tumors^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

20339  [NCBI]

NP_035475.1

ELISA, FACS, Functional assay, Research in vivo

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

[Anti-Mouse E-selectin/CD62E Antibody (9A9)]

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Immler R, et al. Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo. Front Immunol. 2020 Dec 22;11:588245.  [Content Brief]

  [2]. Riera-Domingo C, et al. Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding. Sci Adv. 2023 Mar 22;9(12):eadd5028.  [Content Brief]