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  4. CD8 alpha Antibody(YA6867)

CD8 alpha Antibody(YA6867)

Cat. No.: HY-P87176
User Guide for Antibodies Technical Support

CD8 alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 26 kDa, targeting to CD8 alpha. It can be used for WB,IHC-P,IHC-P,IF-tissue assays with tag free, in the background of mouse.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CD8 alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 26 kDa, targeting to CD8 alpha. It can be used for WB,IHC-P,IHC-P,IF-tissue assays with tag free, in the background of mouse.

Background

CD8 alpha: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Gene ID
SwissProt ID
Synonyms
CD8A; MAL; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD antigen CD8a
Molecular Weight

Predicted band size: 26 kDa;Observed band size: 35 kDa

Purity

affinity purified

Subcellular Location

Membrane; Single-pass type I membrane protein.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Monoclonal, Recombinant

Host

Rabbit

Reactivity

Mouse

Dilution Ratio

WB: 1:500-2000; IHC-P: 1:100-500; IHC-F: 1:100-500; IF-Tissue: 1:100-500

Application

WB, IHC-P, IHC-F, IF-Tissue

Appearance

Liquid

Formulation

Supplied in PBS, Glycerol, BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Immunogen

KLH conjugated synthetic peptide derived from human CD8 alpha.

Database
Documentation

CD8 alpha Antibody(YA6867) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CD8 alpha Antibody(YA6867)
Cat. No.:
HY-P87176
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