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  4. KIR3DL3/CD158z Protein, Cynomolgus (HEK293, His)

KIR3DL3/CD158z Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P703853
Handling Instructions Technical Support

KIR3DL3/CD158z Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived KIR3DL3/CD158z protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

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Description

KIR3DL3/CD158z Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived KIR3DL3/CD158z protein, expressed by HEK293, with C-His tag.
Background

KIR3DL3, present on natural killer cells, acts as a receptor that potentially inhibits NK cell activity, thereby contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating the functions of NK cells and maintaining immune homeostasis.
Species

Cynomolgus
Source

HEK293
Tag

C-His
Accession

XP_005590394.1 (H22-L339)
Gene ID

102144764
Protein Length

Partial
Synonyms
Killer cell immunoglobulin-like receptor 3DL3; CD158Z; KIR3DL7; KIRC1; killer cell immunoglobulin like receptor; three Ig domains and long cytoplasmic tail 3
Predicted Molecular Mass
36 kDa
Molecular Weight

Approximately 51.9 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

KIR3DL3/CD158z Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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