2. GPCR/G Protein Immunology/Inflammation
  3. CXCR Interleukin Related
  4. Elubrixin tosylate (Standard)

Elubrixin tosylate (Standard) 

Cat. No.: HY-18263CR Purity: ≥98%
Handling Instructions Technical Support

Elubrixin (tosylate) (Standard) is the analytical standard of Elubrixin (tosylate). This product is intended for research and analytical applications. Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation.

For research use only. We do not sell to patients.

Elubrixin tosylate (Standard) Chemical Structure

Elubrixin tosylate (Standard) Chemical Structure

CAS No. : 960495-43-6

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Description
Molecular Weight

635.51

Formula

C24H25Cl2FN4O7S2
CAS No.
SMILES

O=C(NC1=CC=C(Cl)C(S(=O)(N2CCNCC2)=O)=C1O)NC3=CC=CC(F)=C3Cl.OS(=O)(C4=CC=C(C)C=C4)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Elubrixin tosylate (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elubrixin tosylate (Standard)960495-43-6CXCRInterleukin RelatedCXC chemokine receptorsC-X-C motif chemokine receptorsILIL-8CXCR2neutrophil-mediatedCD11bairwayanti-inflammatorybowelInhibitorinhibitorinhibit

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