2. Disease Areas
  3. Inflammation or Immune System Disease

Inflammation or Immune System Disease

Inflammation or immune system diseases involve a cascade of events starting with acute inflammation, progressing to chronic inflammation, and culminating in granulation tissue formation and fibrous capsule development around an implant, driven by a foreign body reaction characterized by the accumulation of macrophages and foreign body giant cells at the biomaterial-tissue interface. Inflammation and immune system diseases involve dysregulation of the body's immune responses, leading to excessive or inappropriate activation of immune defenses. These conditions can result from autoimmune disorders, where the immune system attacks self-tissues, or chronic inflammatory states that cause tissue damage and dysfunction. Immunology, the study of the immune system, focuses on understanding the mechanisms underlying immunity and host defense against pathogens like viruses, bacteria, fungi, and parasites, providing insights into the pathogenesis and treatment of immune-related disorders.

 

Inflammation or Immune System Disease (6):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0385
    Gomisin J 66280-25-9 99.97%
    Gomisin J is a Schisandra chinensis-derived lignan that can inhibit multiple targets such as eNOS, AMPK (LKB1, CaMKIIβ), fetuin-A, NF-κB, Nrf2/HO-1, and can pass through the blood-brain barrier. Gomisin J increases NO bioavailability by activating eNOS, regulates lipid metabolism by activating the AMPK pathway, inhibits fetuin-A and NF-κB to exert anti-inflammatory effects, and activates Nrf2/HO-1 to enhance antioxidant capacity. Gomisin J has the activities of anti-hypertension, regulating liver lipid metabolism, and reducing cerebral ischemia-reperfusion injury, and can be used for research on hypertension, non-alcoholic fatty liver disease, cerebral ischemia-reperfusion injury, etc.
    Gomisin J
  • HY-18706
    trans-Tranilast 70806-55-2 98.99%
    trans-Tranilast (trans-MK-341) is an anti-allergy agent used in studies of bronchial asthma, allergic rhinitis, and atopic dermatitis.
    trans-Tranilast
  • HY-B1365
    Prednicarbate 73771-04-7 99.81%
    Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis.
    Prednicarbate
  • HY-106262
    Delcasertib 949100-39-4 98.21%
    Delcasertib (KAI-9803) is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI).
    Delcasertib
  • HY-P99886
    Pexelizumab 219685-93-5
    Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction.
    Pexelizumab
  • HY-132180
    Seco-DUBA hydrochloride 1795733-93-5
    Seco-DUBA hydrochloride is a toxin for ADC drug SYD985.
    Seco-DUBA hydrochloride