2. Immunology/Inflammation
  3. CD3 CD20 Transmembrane Glycoprotein
  4. Anafiltamig

Anafiltamig is a trivalent monoclonal antibody inhibitor targeting CD79B, CD3E and MS4A1. Anafiltamig consists of a humanized IgG1κ anti-CD79B arm and a bispecific scFv-based arm targeting CD3E and MS4A1. Anafiltamig simultaneously bridges T and B cells, activating T cells and specifically killing B cell tumors. Anafiltamig can be used for B cell malignancies such as non-Hodgkin lymphoma research.

For research use only. We do not sell to patients.

Anafiltamig

Anafiltamig Chemical Structure

CAS No. : 3009026-69-8

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Anafiltamig Related Antibodies

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Description

Anafiltamig is a trivalent monoclonal antibody inhibitor targeting CD79B, CD3E and MS4A1. Anafiltamig consists of a humanized IgG1κ anti-CD79B arm and a bispecific scFv-based arm targeting CD3E and MS4A1. Anafiltamig simultaneously bridges T and B cells, activating T cells and specifically killing B cell tumors. Anafiltamig can be used for B cell malignancies such as non-Hodgkin lymphoma research[1][2].

Isotype

immunoglobulin (H-gamma1_L-kappa)_(scFvkh-G1(h-CH2-CH3)-20mer-scFvkh)
Species Reactivity

Human
IC50 & Target

CD79B & CD3E &CD20/MS4A1
Gene ID

974  [NCBI] & 916  [NCBI] & 931  [NCBI]

Accession
Target

CD79B & CD3E &CD20/MS4A1
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
CAS No.
SMILES

N/A
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anafiltamig Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anafiltamig3009026-69-8CD3CD20Transmembrane GlycoproteinCluster of differentiation 3CD79BCD3EMS4A1TrivalentMonoclonal antibodyT cellsB cell malignanciesNon-Hodgkin lymphomaInhibitorinhibitorinhibit

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