2. Immunology/Inflammation
  3. C-type Lectin-like Receptors (CTLRs)
  4. Anti-Mouse NKG2AB6 Antibody (16A11)

Anti-Mouse NKG2AB6 Antibody (16A11) 

Cat. No.: HY-P990179
Technical Support

Anti-Mouse NKG2AB6 Antibody (16A11) is an anti-mouse NKG2AB6 IgG2b monoclonal antibody. Anti-Mouse NKG2AB6 Antibody (16A11) reduces depletion of antigen-specific CD8 T cells. Anti-Mouse NKG2AB6 Antibody (16A11) can be used for research on cancer such as lung cancer and colon cancer.

For research use only. We do not sell to patients.

Anti-Mouse NKG2AB6 Antibody (16A11)

Anti-Mouse NKG2AB6 Antibody (16A11) Chemical Structure

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Anti-Mouse NKG2AB6 Antibody (16A11) Related Antibodies

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Description

Anti-Mouse NKG2AB6 Antibody (16A11) is an anti-mouse NKG2AB6 IgG2b monoclonal antibody. Anti-Mouse NKG2AB6 Antibody (16A11) reduces depletion of antigen-specific CD8 T cells. Anti-Mouse NKG2AB6 Antibody (16A11) can be used for research on cancer such as lung cancer and colon cancer[1][2].

Isotype

Mouse IgG2b kappa
Recommend Isotype Controls
Species Reactivity

Mouse
In Vitro

Anti-Mouse NKG2AB6 Antibody (16A11) (10 μg/mL) does not significantly alter Th1 cell differentiation or IFN-γ secretion[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse NKG2AB6 Antibody (16A11) Related Antibodies
In Vivo

Anti-Mouse NKG2AB6 Antibody (16A11) (200 μg, i.v., twice a week, for 2 weeks) can prolong survival period in female C57BL/6J mice bearing TC-1 or MC-38 tumors[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 1×105 TC-1 or 2×105 MC-38 cells injected female C57BL/6J mice (6-8 weeks)[1]
Dosage: 200 μg
Administration: Intravenous injection (i.v.), twice a week, for 2 weeks
Result: Significantly increased the complete remission rate to 57 %.
Extended survival by 28 days.
Reduced CD8 T cell exhaustion within tumors without increasing functional markers.
Inhibited the number and effector memory differentiation of peripheral antigen-specific CD8 T cells.
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

SMILES

[Anti-Mouse NKG2AB6 Antibody (16A11)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-Mouse NKG2AB6 Antibody (16A11) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse NKG2AB6 Antibody (16A11)C-type Lectin-like Receptors (CTLRs)NKG2AB6CD8T cellsTC-1MC-38Inhibitorinhibitorinhibit

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