MTSSL-¹⁵N,d₁₅  (Synonyms: Otmpmms-¹⁵N,d₁₅)

MTSSL-¹⁵N,d₁₅-1 (Otmpmms-¹⁵N,d₁₅) is the deuterium and ¹⁵N-labeled MTSSL (HY-130509). MTSSL (Otmpmms) is highly reactive thiol-specific spin label, which is used to label protein thiol residues for protein structure and dynamics determination and protein-protein interaction studies^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

280.47

C₁₀H₃D₁₅¹⁵NO₃S₂^*

384342-58-9

81213-52-7

[O][15N]1C(C([2H])([2H])[2H])(C(C([2H])(SS(C)(=O)=O)[2H])=C(C1(C([2H])([2H])[2H])C([2H])([2H])[2H])[2H])C([2H])([2H])[2H]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Watanabe Y, et al., Identification of pH-sensitive regions in the mouse prion by the cysteine-scanning spin-labeling ESR technique. Biochem Biophys Res Commun. 2006 Nov 24;350(3):549-56.  [Content Brief]