Azasetron Hydrochloride-¹³C,d₃ 

Azasetron Hydrochloride-¹³C,d₃ is the deuterium and ¹³C-labeled Azasetron (HY-B0019). Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

390.28

C₁₆¹³CH₁₈D₃Cl₂N₃O₃

1329611-23-5

123040-69-7

[2H][13C]([2H])(N1C(COC2=C1C=C(Cl)C=C2C(NC3CN4CCC3CC4)=O)=O)[2H].Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Effects of ondansetron, granisetron, ramosetron, and azasetron on human neutrophil functions  [Content Brief]