CD24 Protein-VLP, Human (HEK293)

CD24 Protein-VLP, Human (HEK293) is recommended for animal immunization. May have binding signals with Anti-His antibodies.

The CD24 protein is implicated in playing a pivotal role in the cell differentiation of various cell types, with its signaling potentially triggered by the binding of a lectin-like ligand to CD24 carbohydrates, transduced through the release of second messengers derived from the GPI-anchor. CD24 also functions in modulating B-cell activation responses, promoting AG-dependent proliferation of B-cells, and preventing their terminal differentiation into antibody-forming cells. In association with SIGLEC10, CD24 may contribute to the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70, and HSP90, suggesting a role in immune regulation. Additionally, CD24 is implicated in the control of autoimmunity. It exhibits cell-type-specific interactions with LYN and FGR, binding to FRG in a small cell cancer line, LYN in the erythroleukemia cell line K-562, and in Burkitt's lymphoma, highlighting its diverse involvement in cellular processes and immune regulation.

Immobilized Human CD24 VLP at 0.5 μg/mL(100 μl/Well) on the plate. Dose response curve for Anti-CD24 Antibody, hFc Tag with the EC₅₀ of <22.1 ng/mL determined by ELISA.

Human

HEK293

Tag Free

P25063-1 (S27-G59)

100133941  [NCBI]

Full Length of Isoform-1 Mature Peptide

SETTTGTSSNSSQSTSNSGLAPNPTNATTKAAG

Approximately 5.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Solution.

Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.