Glycyl-Exatecan-d₅ hydrochloride  (Synonyms: Glycyl-DX-8951-d₅ hydrochloride; Exatecan analog 2-d₅ hydrochloride)

Glycyl-Exatecan-d₅ (Glycyl-DX-8951-d₅) hydrochloride is deuterium labeled Glycyl-Exatecan (HY-128995A). Glycyl-Exatecan (Glycyl-DX-8951), a derivative of Exatecan (HY-13631), is an anticancer agent. Glycyl-Exatecan has significantly antitumor activity. Glycyl-Exatecan can be used for cancers like solid tumors research.

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

533.99

C₂₆H₂₁D₅ClFN₄O₅

1883333-57-0

Solid

Light yellow to yellow

FC(C=C1N=C2C3=CC([C@](O)4C(C([2H])([2H])[2H])([2H])[2H])=C5COC4=O)=C(C)C6=C1C([C@@H](NC(CN)=O)CC6)=C2CN3C5=O.[H]Cl

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)