CD41 Antibody (YA5367)

CD41 Antibody (YA5367) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD41. It can be applicated for IHC-P, ICC/IF assays, in the background of human.

CD41, also known as integrin alpha-IIb/beta-3, serves as a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, and vitronectin. It recognizes the R-G-D sequence in a broad range of ligands and specifically binds to the H-H-L-G-G-G-A-K-Q-A-G-D-V sequence in the fibrinogen gamma chain (By similarity). Upon activation, integrin alpha-IIb/beta-3 facilitates platelet-platelet interactions by binding soluble fibrinogen (PubMed:9111081), leading to rapid platelet aggregation that physically seals damaged endothelial surfaces (By similarity).

P08514

Predicted band size: 113 kDa;

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

IHC: 1:100; ICC/IF: 1:50-200

IHC-P, ICC/IF

Liquid

Supplied in PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Synthetic Peptide of CD41