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  5. MDR1 Antibody (YA5747)

MDR1 Antibody (YA5747)

Cat. No.: HY-P86055
User Guide for Antibodies Technical Support

MDR1 Antibody (YA5747) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MDR1. It can be applicated for IHC-P, ELISA assays, in the background of human, mouse.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

MDR1 Antibody (YA5747) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MDR1. It can be applicated for IHC-P, ELISA assays, in the background of human, mouse.
Background

MDR1 is a membrane transporter primarily responsible for translocating drugs and phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane (by similar). It mainly facilitates the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides, and sphingomyelins. Additionally, MDR1 functions as an energy-dependent efflux pump, contributing to reduced drug accumulation in multidrug-resistant cells.
Gene ID
SwissProt ID
Synonyms
ABC20; ABCB1; ATP binding cassette, sub family B; MDR/TAP; , member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1
Molecular Weight

Predicted band size: 141 kDa; Observed band size: 120 kDa
Purity

affinity chromatography.
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Reactivity

Human, Mouse,

Dilution Ratio

IHC: 1:200-400; ELISA: 1:500-5000
Application

IHC-P, ELISA
Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG1
Immunogen

Synthesized peptide derived from human MDR1 AA range: 600-700
Documentation
User Guide for Antibodies (1077 KB)

MDR1 Antibody (YA5747) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MDR1 Antibody (YA5747)
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