2. Immunology/Inflammation
  3. MHC
  4. VMAPRTLFL

VMAPRTLFL is a 9-mer peptide derived from the signal peptide of HLA-G and can serve as a peptide ligand for HLA-E. VMAPRTLFL plays a crucial role in regulating the functions of adaptive natural killer (NK) cells. Specifically, VMAPRTLFL enriches FcεRγ- adaptive NK cells, upregulates the expression of CD25, and enhances their proliferative activity, antibody-dependent cellular cytotoxicity (ADCC), and IFN-γ release. VMAPRTLFL can be used in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity.

For research use only. We do not sell to patients.

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VMAPRTLFL

VMAPRTLFL Chemical Structure

CAS No. : 202657-61-2

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VMAPRTLFL Related Antibodies

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MHC I MHC II

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Description

VMAPRTLFL is a 9-mer peptide derived from the signal peptide of HLA-G and can serve as a peptide ligand for HLA-E. VMAPRTLFL plays a crucial role in regulating the functions of adaptive natural killer (NK) cells. Specifically, VMAPRTLFL enriches FcεRγ- adaptive NK cells, upregulates the expression of CD25, and enhances their proliferative activity, antibody-dependent cellular cytotoxicity (ADCC), and IFN-γ release. VMAPRTLFL can be used in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity[1].

IC50 & Target[1]

MHC I

 

Molecular Weight

1047.31

Formula

C49H82N12O11S
CAS No.
Sequence

Val-Met-Ala-Pro-Arg-Thr-Leu-Phe-Leu
Sequence Shortening

VMAPRTLFL
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VMAPRTLFL Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VMAPRTLFL202657-61-2MHCMajor Histocompatibility ComplexNK cellsInhibitorinhibitorinhibit

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