2. Recombinant Proteins
  3. Cytokines and Growth Factors CD Antigens Receptor Proteins Enzymes & Regulators
  4. PDGFs & PDGFRs Platelet CD Proteins Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. PDGF-R-alpha PDGFR
  6. PDGF-R-alpha
  7. PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His)

PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His)

Cat. No.: HY-P700809
Handling Instructions Technical Support

PDGF R alpha Protein, a tyrosine-protein kinase receptor, crucially influences embryonic development, regulating cell proliferation, survival, and chemotaxis. Its effects on cell behavior vary contextually, either promoting or inhibiting proliferation and migration. Additionally, it plays a significant role in differentiating bone marrow-derived mesenchymal stem cells and is essential for normal skeletal development. PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) is the recombinant cynomolgus-derived PDGF R alpha protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PDGF R alpha Protein, a tyrosine-protein kinase receptor, crucially influences embryonic development, regulating cell proliferation, survival, and chemotaxis. Its effects on cell behavior vary contextually, either promoting or inhibiting proliferation and migration. Additionally, it plays a significant role in differentiating bone marrow-derived mesenchymal stem cells and is essential for normal skeletal development. PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) is the recombinant cynomolgus-derived PDGF R alpha protein, expressed by HEK293 , with C-His labeled tag.
Background

PDGF R alpha Protein is a tyrosine-protein kinase that serves as a cell-surface receptor for PDGFA, PDGFB, and PDGFC. It plays a crucial role in embryonic development, regulating cell proliferation, survival, and chemotaxis. Its function can either promote or inhibit cell proliferation and migration, depending on the context. Additionally, it plays a significant role in the differentiation of mesenchymal stem cells derived from the bone marrow. Furthermore, PDGF R alpha Protein is essential for normal skeletal development.
Species

Cynomolgus
Source

HEK293
Tag

C-8*His
Accession

Q0PW86 (Q24-E524)
Gene ID

102138392
Molecular Construction
N-term
PDGF R alpha (Q24-E524)
Accession # Q0PW86
8*His
C-term
Protein Length

Partial
Synonyms
PDGFRA; CD140A; PDGFR2; RHEPDGFRA; MGC74795; PDGFR-2
Predicted Molecular Mass
57.3 kDa
Molecular Weight

Approximately 70-85 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His)
Cat. No.:
HY-P700809
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.