1. Immunology/Inflammation Metabolic Enzyme/Protease
  2. CD73 Phosphodiesterase (PDE) Phosphatase
  3. CD73-IN-20

CD73-IN-20 (Compound 5c) is an e5′NT (CD73) inhibitor (IC50: 0.37 μM). CD73-IN-20 also inhibits other ectonucleotidases, with IC50s of 1.12 μM (h-ENPP1), 1.37 μM (h-ENPP3), 1.66 μM (r-e5′NT), 1.48 μM (h-TNAP), respectively. CD73-IN-20 can be used for cancer research.

For research use only. We do not sell to patients.

CD73-IN-20

CD73-IN-20 Chemical Structure

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Description

CD73-IN-20 (Compound 5c) is an e5′NT (CD73) inhibitor (IC50: 0.37 μM). CD73-IN-20 also inhibits other ectonucleotidases, with IC50s of 1.12 μM (h-ENPP1), 1.37 μM (h-ENPP3), 1.66 μM (r-e5′NT), 1.48 μM (h-TNAP), respectively. CD73-IN-20 can be used for cancer research[1].

Molecular Weight

424.44

Formula

C22H17FN2O4S

SMILES

O=C(CC1=CNC2=CC=CC=C21)NC3=CC=CC=C3OS(C4=CC=C(C=C4)F)(=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD73-IN-20
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HY-172527
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